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. 1988 Jan;41(1):17–20. doi: 10.1136/jcp.41.1.17

Ultrastructural and immunocytochemical study of a case of invasive cribriform breast carcinoma.

C A Wells 1, D J Ferguson 1
PMCID: PMC1141328  PMID: 3343375

Abstract

A case of recurrent invasive cribriform carcinoma of the breast mimicked the histological and mucin staining characteristics of adenoid cystic carcinoma. The diagnosis was based on negative immunocytochemical staining for laminin and ultrastructural evidence of luminal differentiation by cells lining the cystic spaces. Accurate characterisation of this type of breast tumour can be facilitated by retrospective immunocytochemical or ultrastructural examination, or both.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Anthony P. P., James P. D. Adenoid cystic carcinoma of the breast: prevalence, diagnostic criteria, and histogenesis. J Clin Pathol. 1975 Aug;28(8):647–655. doi: 10.1136/jcp.28.8.647. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Ferguson D. J., Anderson T. J., Wells C. A., Battersby S. An ultrastructural study of mucoid carcinoma of the breast: variability of cytoplasmic features. Histopathology. 1986 Dec;10(12):1219–1230. doi: 10.1111/j.1365-2559.1986.tb02566.x. [DOI] [PubMed] [Google Scholar]
  3. Fisher E. R. Ultrastructure of the human breast and its disorders. Am J Clin Pathol. 1976 Aug;66(2):291–375. doi: 10.1093/ajcp/66.2.291. [DOI] [PubMed] [Google Scholar]
  4. Harris M. Pseudoadenoid cystic carcinoma of the breast. Arch Pathol Lab Med. 1977 Jun;101(6):307–309. [PubMed] [Google Scholar]
  5. Page D. L., Dixon J. M., Anderson T. J., Lee D., Stewart H. J. Invasive cribriform carcinoma of the breast. Histopathology. 1983 Jul;7(4):525–536. doi: 10.1111/j.1365-2559.1983.tb02265.x. [DOI] [PubMed] [Google Scholar]
  6. Wells C. A., Nicoll S., Ferguson D. J. Adenoid cystic carcinoma of the breast: a case with axillary lymph node metastasis. Histopathology. 1986 Apr;10(4):415–424. doi: 10.1111/j.1365-2559.1986.tb02494.x. [DOI] [PubMed] [Google Scholar]
  7. d'Ardenne A. J., Kirkpatrick P., Wells C. A., Davies J. D. Laminin and fibronectin in adenoid cystic carcinoma. J Clin Pathol. 1986 Feb;39(2):138–144. doi: 10.1136/jcp.39.2.138. [DOI] [PMC free article] [PubMed] [Google Scholar]

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