Abstract
A fatal rupture of an hepatic tumour occurred in an athlete who had been taking anabolic steroids for several years as an aid to body building. The case illustrates the hazards of non-therapeutic androgen administration, and emphasises the need for athletes to be made clear of the disturbances to gonadal function, liver structure and function, and the threat to life.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Anthony P. P. Letter: hepatoma associated with androgenic steroids. Lancet. 1975 Mar 22;1(7908):685–686. doi: 10.1016/s0140-6736(75)91790-0. [DOI] [PubMed] [Google Scholar]
- Farrell G. C., Joshua D. E., Uren R. F., Baird P. J., Perkins K. W., Kronenberg H. Androgen-induced hepatoma. Lancet. 1975 Feb 22;1(7904):430–432. doi: 10.1016/s0140-6736(75)91494-4. [DOI] [PubMed] [Google Scholar]
- Ishak K. G. Hepatic neoplasms associated with contraceptive and anabolic steroids. Recent Results Cancer Res. 1979;66:73–128. doi: 10.1007/978-3-642-81267-5_3. [DOI] [PubMed] [Google Scholar]
- McCaughan G. W., Bilous M. J., Gallagher N. D. Long-term survival with tumor regression in androgen-induced liver tumors. Cancer. 1985 Dec 1;56(11):2622–2626. doi: 10.1002/1097-0142(19851201)56:11<2622::aid-cncr2820561115>3.0.co;2-0. [DOI] [PubMed] [Google Scholar]
- Paradinas F. J., Bull T. B., Westaby D., Murray-Lyon I. M. Hyperplasia and prolapse of hepatocytes into hepatic veins during longterm methyltestosterone therapy: possible relationships of these changes to the developement of peliosis hepatis and liver tumours. Histopathology. 1977 Jul;1(4):225–246. doi: 10.1111/j.1365-2559.1977.tb01663.x. [DOI] [PubMed] [Google Scholar]
- Westaby D., Portmann B., Williams R. Androgen related primary hepatic tumors in non-Fanconi patients. Cancer. 1983 May 15;51(10):1947–1952. doi: 10.1002/1097-0142(19830515)51:10<1947::aid-cncr2820511034>3.0.co;2-5. [DOI] [PubMed] [Google Scholar]