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. 1988 Jul;41(7):720–721. doi: 10.1136/jcp.41.7.720

Incidence of decreased penicillin sensitivity of Streptococcus pneumoniae from clinical isolates.

P Nair 1
PMCID: PMC1141575  PMID: 3410966

Abstract

One hundred isolates of Streptococcus pneumoniae isolated from clinical specimens over nine months were examined for sensitivity to penicillin using disc tests and minimum inhibitory concentration (MIC) studies. Four per cent of the isolates were found to have reduced sensitivity to penicillin. Penicillin and methicillin discs with 1 unit and 5 micrograms antibiotic, respectively, were inferior to discs with 1 microgram oxacillin, which gave results comparable with those of MIC studies.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Appelbaum P. C. World-wide development of antibiotic resistance in pneumococci. Eur J Clin Microbiol. 1987 Aug;6(4):367–377. doi: 10.1007/BF02013089. [DOI] [PubMed] [Google Scholar]
  2. Feldman C., Kallenbach J. M., Miller S. D., Thorburn J. R., Koornhof H. J. Community-acquired pneumonia due to penicillin-resistant pneumococci. N Engl J Med. 1985 Sep 5;313(10):615–617. doi: 10.1056/NEJM198509053131006. [DOI] [PubMed] [Google Scholar]
  3. Howard A. J., Hince C. J., Williams J. D. Antibiotic resistance in Streptococcus pneumoniae and Haemophilus influenzae. Report of a study group on bacterial resistance. Br Med J. 1978 Jun 24;1(6128):1657–1660. doi: 10.1136/bmj.1.6128.1657. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Howes V. J., Mitchell R. G. Meningitis due to relatively penicillin-resistant pneumococcus. Br Med J. 1976 Apr 24;1(6016):996–996. doi: 10.1136/bmj.1.6016.996. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Jacobs M. R., Gaspar M. N., Robins-Browne R. M., Koornhof H. J. Antimicrobial susceptibility testing of pneumococci. 2. Determination of optimal disc diffusion test for detection of penicillin G resistance. J Antimicrob Chemother. 1980 Jan;6(1):53–64. doi: 10.1093/jac/6.1.53. [DOI] [PubMed] [Google Scholar]
  6. Jones R. N., Edson D. C. The ability of participant laboratories to detect penicillin-resistant Pneumococci. A report from the microbiology portion of the College of American Pathologists (CAP) surveys. Am J Clin Pathol. 1982 Oct;78(4 Suppl):659–663. [PubMed] [Google Scholar]
  7. Kislak J. W., Razavi L. M., Daly A. K., Finland M. Susceptibility of pneumococci to nine antibiotics. Am J Med Sci. 1965 Sep;250(3):261–268. doi: 10.1097/00000441-196509000-00003. [DOI] [PubMed] [Google Scholar]
  8. Kislak J. W. Type 6 pneumococcus resistant to erythromycin and lincomycin. N Engl J Med. 1967 Apr 13;276(15):852–852. doi: 10.1056/NEJM196704132761508. [DOI] [PubMed] [Google Scholar]
  9. Klugman K. P., Koornhof H. J., Wasas A., Storey K., Gilbertson I. Carriage of penicillin resistant pneumococci. Arch Dis Child. 1986 Apr;61(4):377–381. doi: 10.1136/adc.61.4.377. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Pallares R., Gudiol F., Liñares J., Ariza J., Rufi G., Murgui L., Dorca J., Viladrich P. F. Risk factors and response to antibiotic therapy in adults with bacteremic pneumonia caused by penicillin-resistant pneumococci. N Engl J Med. 1987 Jul 2;317(1):18–22. doi: 10.1056/NEJM198707023170104. [DOI] [PubMed] [Google Scholar]
  11. Paton J. H., Reeves D. S. First multiresistant pneumococcus in Britain. Br Med J (Clin Res Ed) 1987 Oct 3;295(6602):810–811. doi: 10.1136/bmj.295.6602.810. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Rees T., Waterworth P. M. A problem with the recognition of penicillin-resistant pneumococci. J Clin Pathol. 1980 Nov;33(11):1092–1094. doi: 10.1136/jcp.33.11.1092. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Swenson J. M., Hill B. C., Thornsberry C. Screening pneumococci for penicillin resistance. J Clin Microbiol. 1986 Nov;24(5):749–752. doi: 10.1128/jcm.24.5.749-752.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]

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