Skip to main content
Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1989 Apr;42(4):378–382. doi: 10.1136/jcp.42.4.378

Histopathological assessment of bleeding from polyps of the colon and rectum.

A Waldock 1, I O Ellis 1, N C Armitage 1, D R Turner 1, J D Hardcastle 1
PMCID: PMC1141908  PMID: 2715351

Abstract

One hundred and twenty seven colorectal polyps were examined to assess histopathological evidence of recent and old haemorrhage to test the usefulness of faecal occult blood tests in detecting colorectal neoplasia, in particular premalignant adenomas. Evidence of haemorrhage was consistently found in adenomas but was rare in non-neoplastic polyps. Haemorrhage within adenomas was predominantly stromal and associated with dilated, congested vessels. Factors associated with more severe haemorrhage were size, pedunculation, and villous growth; the degree of epithelial dysplasia and the age and sex of the patient were not associated factors. Proximal polyps showed more old haemorrhage than rectal polyps, but there was no such difference for recent haemorrhage.

Full text

PDF
378

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Brown L. J., Smeeton N. C., Dixon M. F. Assessment of dysplasia in colorectal adenomas: an observer variation and morphometric study. J Clin Pathol. 1985 Feb;38(2):174–179. doi: 10.1136/jcp.38.2.174. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Greegor D. H. Diagnosis of large-bowel cancer in the asymptomatic patient. JAMA. 1967 Sep 18;201(12):943–945. [PubMed] [Google Scholar]
  3. Herzog P., Holtermüller K. H., Preiss J., Fischer J., Ewe K., Schreiber H. J., Berres M. Fecal blood loss in patients with colonic polyps: a comparison of measurements with 51chromium-labeled erythrocytes and with the Haemoccult test. Gastroenterology. 1982 Nov;83(5):957–962. [PubMed] [Google Scholar]
  4. Konishi F., Morson B. C. Pathology of colorectal adenomas: a colonoscopic survey. J Clin Pathol. 1982 Aug;35(8):830–841. doi: 10.1136/jcp.35.8.830. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Liu K., Mittelman A., Sproul E. E., Elias E. G. Renal toxicity in man treated with mitomycin C. Cancer. 1971 Nov;28(5):1314–1320. doi: 10.1002/1097-0142(1971)28:5<1314::aid-cncr2820280534>3.0.co;2-d. [DOI] [PubMed] [Google Scholar]
  6. Macrae F. A., St John D. J. Relationship between patterns of bleeding and Hemoccult sensitivity in patients with colorectal cancers or adenomas. Gastroenterology. 1982 May;82(5 Pt 1):891–898. [PubMed] [Google Scholar]
  7. Simon J. B. Occult blood screening for colorectal carcinoma: a critical review. Gastroenterology. 1985 Mar;88(3):820–837. doi: 10.1016/0016-5085(85)90158-1. [DOI] [PubMed] [Google Scholar]
  8. Sobin L. H. The histopathology of bleeding from polyps and carcinomas of the large intestine. Cancer. 1985 Feb 1;55(3):577–581. doi: 10.1002/1097-0142(19850201)55:3<577::aid-cncr2820550317>3.0.co;2-d. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Publishing Group

RESOURCES