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. 2024 Sep 13;11:1489092. doi: 10.3389/fmed.2024.1489092

Corrigendum: Efficacy and safety of Janus kinase inhibitors in non-infectious inflammatory ocular diseases: a prospective cohort study from the international AIDA network registries

Antonio Vitale 1,2,, Judith Palacios-Olid 3,, Valeria Caggiano 1,2, Gaafar Ragab 4,5, José Hernández-Rodríguez 6, Laura Pelegrín 6, Germán Mejía-Salgado 7, Laura Zarate-Pinzón 7, Stefano Gentileschi 1,2, Jurgen Sota 1,2, Alex Fonollosa 8, Ester Carreño 9,10, Carla Gaggiano 1,2, Rana Hussein Amin 11, Alberto Balistreri 2,12, Javier Narváez 3, Gian Marco Tosi 13, Bruno Frediani 1,2, Luca Cantarini 1,2,*, Alejandra de-la-Torre 7, Claudia Fabiani 2,13,*
PMCID: PMC11427952  PMID: 39346944

In the published article, there was an error in Figure 1 as published. In the Figure 1 there are several errors in the panels, which are crucial for the selection of patients included in the study. “Uveitis registry” was changed to “AIDA registry”; “Behçet's disease” was removed from the middle right hand side panel; “Behçet's disease patients with ocular involvement treated with JAK inhibitors” was changed to “Patients treated with JAK inhibitors” in the bottom right hand side panel. The corrected Figure 1 and its caption appear below.

Figure 1.

Figure 1

Flow-chart explaining the selection of patients included in this study starting from the total number of patients included in the AutoInflammatory Disease Alliance (AIDA) Network project.

In the published article, there was an error in Table 1 as published. In Table 1, there is a typographical error in the second to last row, “Extra ocular” was changed to “Extraocular”. The corrected Table 1 and its caption appear below.

Table 1.

Demographic, clinical and therapeutic features describing the twelve patients enrolled.

Sex Age at ocular disease onset, years Age at diagnosis, years Ocular diagnosis Systemic or oculo-specific diagnosis Treatment performed Age at the start of treatment, years Main reason for starting JAK inhibitors Treatment duration, months GCs at start, mg/day GCs at last assessment, mg/day
Female 33 35 Posterior uveitis (multifocal choroiditis) Punctate inner choroidopathy Upadacitinib 15 mg/day plus leflunomide 20 mg/day 38.5 Ocular activity 6 0 0
Female 51.2 51.4 Pars planitis Idiopathic Upadacitinib 15 mg/day 54.2 Ocular activity 20 0 0
Female 81.2 81.2 Anterior uveitis (iridocyclitis) Idiopathic Upadacitinib 15 mg/day plus azathioprine 200 mg/day 83.3 Ocular activity 3 Sub-tenon corticosteroids 0
Male 29.8 36.3 Anterior uveitis (iridocyclitis) Seronegative spondyloarthritis Upadacitinib 15 mg/day 57 Extraocular activity 3 0 0
Female 40.9 40.9 Panuveitis Seronegative spondyloarthritis Upadacitinib 15 mg/day 49.5 Ocular activity 6 0 0
Female 59.2 59.2 Anterior sclerouveitis Rheumatoid arthritis Baricitinib 2 mg/day 61 Both ocular and extraocular activity 17 PDN 15 0
Male 12.8 13.8 Panuveitis Vogt-Koyanagi-Harada syndrome Baricitinib 4 mg/day 19.9 Ocular activity 7 PDN 15 7.5 PDN
Female 29 29 Posterior uveitis (multifocal choroiditis) Idiopathic Baricitinib 4 mg/day 45.2 Ocular activity 3 PDN 30 12.5 PDN
Male 32.5 39 Anterior uveitis Behçet's syndrome Upadacitinib 15 mg/day plus azathioprine 200 mg/day 57 Ocular activity 11 Peribulbar corticosteroid injections 0
Male 44 44 Anterior scleritis, posterior scleritis Psoriatic arthritis Upadacitinib 15 mg/day plus sulfasalazine 1,000 mg/day 50 Both ocular and extraocular activity 7 0 0
Female 22.6 22.6 Anterior uveitis (iridocyclitis) Seronegative spondyloarthritis Tofacitinib 10 mg/die 57.8 Extraocular activity 8 PDN 50 0
Male 2.5 2.6 Anterior uveitis ANA positive juvenile idiopathic arthritis Baricitinib 4 mg/day 26.5 Both ocular and extraocular activity 12 0 0

Each row is referred to one patient.

ANA, anti-nuclear autoantibodies; GCs, glucocorticoids; JAK, Janus Kinase; PDN, prednisone.

In the published article, there was an error. There are four sentences in which there are either structural or typographical errors.

A correction has been made to Patients and methods, Paragraph 1. This sentence previously stated:

“international AutoInflammatory Disease Alliance (AIDA) Network registries dedicated to uveitis, scleritis and Behçet's disease”.

The corrected sentence appears below:

“International AutoInflammatory Disease Alliance (AIDA) Network registries dedicated to uveitis, scleritis and Behçet's syndrome”.

A correction has been made to Results, Paragraph 1. This sentence previously stated:

“and one from the International AIDA Network registry dedicated to Behçet's disease (10)”.

The corrected sentence appears below:

“and one from the International AIDA Network registry dedicated to Behçet's syndrome (10)”.

A correction has been made to Treatment details, Paragraph 8. This sentence previously stated:

“Four patients were receiving combination therapy with cDMARDs at the start of treatment with JAK inhibitors: two were on azathioprine, and one on sulfasalazine. The follow-up period while on combination therapy was three months and eleven months for the patients on azathioprine, and seven months for the patient treated with sulfasalazine”.

The corrected sentence appears below:

“Four patients were receiving combination therapy with cDMARDs at the start of treatment with JAK inhibitors: two were on azathioprine, one was on leflunomide, and one was on sulfasalazine. The follow-up period while on combination therapy was three months and eleven months for the patients on azathioprine, seven months for the patient in therapy with sulfasalazine, and six months for the patient treated with leflunomide”.

A correction has been made to Discussion, Paragraph 6. This sentence previously stated:

“The lack of Gas withdrawal in these two cases was either due to systemic disease activity or the short follow-up duration”.

The corrected sentence appears below:

“The lack of GCs withdrawal in these two cases was either due to systemic disease activity or the short follow-up duration”.

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Publisher's note

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