Table 1. Baseline demographic and clinical characteristics of patients and among cirrhotic, and non-cirrhotic groups.
Variables | Subgroups | Total (N=53) | Cirrhosis (N= 13, 24.5%) | Noncirrhotic (N= 40; 75.5%) | p-value |
Age (year)a | Mean ± SD | 50.0 ± 15.3 | 61.7 ± 6.9 | 46.2 ± 15.4 | 0.001 |
Genderb | Male | 17 (32.1) | 6 (46.2) | 11 (27.5) | 0.363 |
Female | 36 (67.9) | 7 (53.8) | 29 (72.5) | ||
Hypertensionb | No | 44 (83.0) | 9 (69.2) | 35 (87.5) | 0.272 |
Yes | 9 (17.0) | 4 (30.8) | 5 (12.5) | ||
Diabetesb | No | 41 (77.4) | 8 (61.5) | 33 (82.5) | 0.235 |
Yes | 12 (22.6) | 5 (38.5) | 7 (17.5) | ||
Fatty liverb | No | 45 (84.9) | 13 (100.0) | 32 (80.0) | 0.192 |
Yes | 8 (15.1) | 0 (0.0) | 8 (20.0) | ||
Pretreatment ALT (U/L)a | Mean ± SD | 39.6 ± 18.9 | 51.6 ± 21.2 | 35.6 ± 16.6 | 0.007 |
Pretreatment AST (U/L)a | Mean ± SD | 37.1 ± 21.9 | 48.9 ± 27.1 | 33.2 ± 18.7 | 0.023 |
Pretreatment TB (mg/dL)a | Mean ± SD | 0.8 ± 0.2 | 0.9 ± 0.2 | 0.8 ± 0.2 | 0.140 |
Pretreatment ALP (IU/L)a | Mean ± SD | 3.6 ± 0.4 | 3.3 ± 0.4 | 3.6 ± 0.4 | 0.012 |
Pretreatment Viral load (HCV RNA, log10 IU/mL)a | Mean ± SD | 9912154.4 ± 37597461.8 | 14171118.5 ± 36691688.8 | 8527991.1 ± 38242745.0 | 0.643 |
Pretreatment Viral load (HCV RNA, log10 IU/mL)b | <800000 | 32 (60.4) | 10 (76.9) | 22 (55.0) | 0.281 |
>800000 | 21 (39.6) | 3 (23.1) | 18 (45.0) |