Skip to main content
Biochemical Journal logoLink to Biochemical Journal
. 1984 Jul 1;221(1):27–31. doi: 10.1042/bj2210027

Low-frequency vibrations of DNA molecules.

K C Chou
PMCID: PMC1143999  PMID: 6466317

Abstract

A model for calculating the low-frequency modes in DNA molecules is presented. The present model is associated with the 'breathing' of a DNA molecule as well as its complementary hydrogen bonds. The calculated results show excellent agreement with the observed low-frequency wavenumber (30 cm-1). Consequently, such an internal motion as reflected in the proposed model might be the origin of the observed low-frequency vibration in DNA molecules. This is helpful for investigating the relevant biological functions, which so far have been discussed by many scientists.

Full text

PDF
27

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Brown K. G., Erfurth S. C., Small E. W., Peticolas W. L. Conformationally dependent low-frequency motions of proteins by laser Raman spectroscopy. Proc Natl Acad Sci U S A. 1972 Jun;69(6):1467–1469. doi: 10.1073/pnas.69.6.1467. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Careri G., Fasella P., Gratton E. Statistical time events in enzymes: a physical assessment. CRC Crit Rev Biochem. 1975 Aug;3(2):141–164. doi: 10.3109/10409237509102555. [DOI] [PubMed] [Google Scholar]
  3. Chou K. C. Identification of low-frequency modes in protein molecules. Biochem J. 1983 Dec 1;215(3):465–469. doi: 10.1042/bj2150465. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Chou K. C. Low-frequency vibrations of helical structures in protein molecules. Biochem J. 1983 Mar 1;209(3):573–580. doi: 10.1042/bj2090573. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Fanconi B., Small E. W., Peticolas W. L. Phonon dispersion curves and normal coordinate analysis of -poly-L-alanine. Biopolymers. 1971;10(8):1277–1298. doi: 10.1002/bip.360100804. [DOI] [PubMed] [Google Scholar]
  6. Genzel L., Keilmann F., Martin T. P., Winterling G., Yacoby Y., Fröhlich H., Makinen M. W. Low-frequency Raman spectra of lysozyme. Biopolymers. 1976 Jan;15(1):219–225. doi: 10.1002/bip.1976.360150115. [DOI] [PubMed] [Google Scholar]
  7. Ito K., Shimanouchi T. Vibrational frequencies and modes of alpha-helix. Biopolymers. 1970;9(4):383–399. doi: 10.1002/bip.1970.360090402. [DOI] [PubMed] [Google Scholar]
  8. Ji S. Energy and negentropy in enzymic catalysis. Ann N Y Acad Sci. 1974 Feb 18;227:419–437. doi: 10.1111/j.1749-6632.1974.tb14405.x. [DOI] [PubMed] [Google Scholar]
  9. Mandal C., Kallenbach N. R., Englander S. W. Base-pair opening and closing reactions in the double helix. A stopped-flow hydrogen exchange study in poly(rA).poly(rU). J Mol Biol. 1979 Dec 5;135(2):391–411. doi: 10.1016/0022-2836(79)90443-1. [DOI] [PubMed] [Google Scholar]
  10. Manning G. S. Breathing and bending fluctuations in DNA modeled by an open-base-pair kink coupled to axial compression. Biopolymers. 1983 Feb;22(2):689–729. doi: 10.1002/bip.360220211. [DOI] [PubMed] [Google Scholar]
  11. Painter P. C., Mosher L. E., Rhoads C. Low-frequency modes in the Raman spectra of proteins. Biopolymers. 1982 Jul;21(7):1469–1472. doi: 10.1002/bip.360210715. [DOI] [PubMed] [Google Scholar]
  12. Sobell H. M., Lozansky E. D., Lessen M. Structural and energetic considerations of wave propagation in DNA. Cold Spring Harb Symp Quant Biol. 1979;43(Pt 1):11–19. doi: 10.1101/sqb.1979.043.01.004. [DOI] [PubMed] [Google Scholar]
  13. Suezaki Y., Go N. Breathing mode of conformational fluctuations in globular proteins. Int J Pept Protein Res. 1975;7(4):333–334. doi: 10.1111/j.1399-3011.1975.tb02448.x. [DOI] [PubMed] [Google Scholar]

Articles from Biochemical Journal are provided here courtesy of The Biochemical Society

RESOURCES