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. 1984 Aug 15;222(1):229–233. doi: 10.1042/bj2220229

Incorporation of serine into Paramecium ethanolamine phospholipid and phosphonolipid head groups.

D F Matesic, E S Kaneshiro
PMCID: PMC1144164  PMID: 6433895

Abstract

Ethanolamine phospholipid head groups in Paramecium were synthesized directly from ethanolamine. As in other cell types, radioactivity from ethanolamine failed to incorporate significantly into head groups of ethanolamine phosphonolipids, indicating that the phosphonolipids are not derived from their phospholipid analogues. Unlike other systems previously examined, radioactivity from serine is incorporated into both ethanolamine phospholipid and phosphonolipid head groups of glycerolipids and sphingolipids in this ciliate. These observations suggest that synthesis of ethanolamine phosphonolipids involves synthesis de novo of free phosphonoserine, which is then incorporated into lipids, and then lipid-bound phosphonoserine intermediates (glycerolipids or sphingolipids) undergo decarboxylation, forming lipidbound phosphonoethanolamine compounds.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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