Skip to main content
NCBI home page
Biochemical Journal logoLink to Biochemical Journal
. 1985 Mar 1;226(2):345–360. doi: 10.1042/bj2260345

Regulation of cell proliferation and differentiation by interferons.

M J Clemens, M A McNurlan
PMCID: PMC1144719  PMID: 2581554

Full text

PDF
345

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Adams A., Strander H., Cantell K. Sensitivity of the Epstein-Barr virus transformed human lymphoid cell lines to interferon. J Gen Virol. 1975 Aug;28(2):207–217. doi: 10.1099/0022-1317-28-2-207. [DOI] [PubMed] [Google Scholar]
  2. Attallah A. M., Fleisher T., Khalil R., Noguchi P. D., Urritia-Shaw A. Proliferative and functional aspects of interferon-treated human normal and neoplastic T and B cells. Br J Cancer. 1980 Sep;42(3):423–429. doi: 10.1038/bjc.1980.254. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Baglioni C. Interferon-induced enzymatic activities and their role in the antriviral state. Cell. 1979 Jun;17(2):255–264. doi: 10.1016/0092-8674(79)90151-x. [DOI] [PubMed] [Google Scholar]
  4. Balkwill F., Taylor-Papadimitriou J. Interferon affects both G1 and S+G2 in cells stimulated from quiescence to growth. Nature. 1978 Aug 24;274(5673):798–800. doi: 10.1038/274798a0. [DOI] [PubMed] [Google Scholar]
  5. Balkwill F., Watling D., Taylor-Papadimitriou J. Inhibition by lymphoblastoid interferon of growth of cells derived from the human breast. Int J Cancer. 1978 Sep 15;22(3):258–265. doi: 10.1002/ijc.2910220307. [DOI] [PubMed] [Google Scholar]
  6. Ball L. A. Induction of 2'5'-oligoadenylate synthetase activity and a new protein by chick interferon. Virology. 1979 Apr 30;94(2):282–296. doi: 10.1016/0042-6822(79)90462-8. [DOI] [PubMed] [Google Scholar]
  7. Banerjee D. K., Baksi K., Friedman R. M. Interferon-mediated inhibition of adenylate cyclase in mouse cells. J Interferon Res. 1982;2(4):501–510. doi: 10.1089/jir.1982.2.501. [DOI] [PubMed] [Google Scholar]
  8. Basham T. Y., Bourgeade M. F., Creasey A. A., Merigan T. C. Interferon increases HLA synthesis in melanoma cells: interferon-resistant and -sensitive cell lines. Proc Natl Acad Sci U S A. 1982 May;79(10):3265–3269. doi: 10.1073/pnas.79.10.3265. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Beck G., Poindron P., Illinger D., Beck J. P., Ebel J. P., Falcoff R. Inhibition of steroid inducible tyrosine aminotransferase by mouse and rat interferon in hepatoma tissue culture cells. FEBS Lett. 1974 Nov 15;48(2):297–300. doi: 10.1016/0014-5793(74)80490-4. [DOI] [PubMed] [Google Scholar]
  10. Besançon F., Bourgeade M. F., Justesen J., Ferbus D., Thang M. N. Two inducers of cell differentiation enhance the 2'5' oligoadenylate synthetase activity in MSV transformed cells. Biochem Biophys Res Commun. 1981 Nov 16;103(1):16–24. doi: 10.1016/0006-291x(81)91654-5. [DOI] [PubMed] [Google Scholar]
  11. Borden E. C., Hogan T. F., Voelkel J. G. Comparative antiproliferative activity in vitro of natural interferons alpha and beta for diploid and transformed human cells. Cancer Res. 1982 Dec;42(12):4948–4953. [PubMed] [Google Scholar]
  12. Bourgeade M. F., Chany C. Effect of sodium butyrate on the antiviral and anticellular action of interferon in normal and MSV-transformed cells. Int J Cancer. 1979 Sep 15;24(3):314–318. doi: 10.1002/ijc.2910240307. [DOI] [PubMed] [Google Scholar]
  13. Bourgeade M. F., Rousset S., Paulin D., Chany C. Reorganization of the cytoskeleton by interferon in MSV-transformed cells. J Interferon Res. 1981 Feb;1(2):323–332. doi: 10.1089/jir.1981.1.323. [DOI] [PubMed] [Google Scholar]
  14. Branca A. A., Baglioni C. Evidence that types I and II interferons have different receptors. Nature. 1981 Dec 24;294(5843):768–770. doi: 10.1038/294768a0. [DOI] [PubMed] [Google Scholar]
  15. Branca A. A., D'Alessandro S. B., Baglioni C. Internalization and degradation of human alpha-A interferon bound to bovine MDBK cells: regulation of the decay and resynthesis of receptors. J Interferon Res. 1983;3(4):465–471. doi: 10.1089/jir.1983.3.465. [DOI] [PubMed] [Google Scholar]
  16. Brideau R. J., Stringfellow D. A. Antiproliferative action of interferon on murine L1210 cells: interrelationship with prostaglandins. J Interferon Res. 1983;3(4):409–415. doi: 10.1089/jir.1983.3.409. [DOI] [PubMed] [Google Scholar]
  17. Brouty-Boyé D., Macieira-Coelho A., Fiszman M., Gresser I. Interferon and cell division. 8. Effect of interferon on macromolecular synthesis in L1210 Cells in vitro. Int J Cancer. 1973 Jul 15;12(1):250–258. doi: 10.1002/ijc.2910120126. [DOI] [PubMed] [Google Scholar]
  18. Brouty-Boyé D., Tovey M. G. Inhibition by interferon of thymidine uptake in chemostat cultures of L1210 cells. Intervirology. 1978;9(4):243–252. doi: 10.1159/000148942. [DOI] [PubMed] [Google Scholar]
  19. Burrone O. R., Milstein C. Control of HLA-A,B,C synthesis and expression in interferon-treated cells. EMBO J. 1982;1(3):345–349. doi: 10.1002/j.1460-2075.1982.tb01172.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Butt T. R., Sreevalsan T. Interferon and sodium butyrate inhibit the stimulation of poly(ADP-ribose) synthetase in mouse cells stimulated to divide. Exp Cell Res. 1983 Oct 15;148(2):449–459. doi: 10.1016/0014-4827(83)90166-0. [DOI] [PubMed] [Google Scholar]
  21. Cayley P. J., Kerr I. M. Synthesis, characterisation and biological significance of (2'-5')oligoadenylate derivatives of NAD+, ADP-ribose and adenosine(5')tetraphospho(5')adenosine. Eur J Biochem. 1982 Mar 1;122(3):601–608. [PubMed] [Google Scholar]
  22. Chang E. H., Mims S. J., Triche T. J., Friedman R. M. Interferon inhibits mouse leukaemia virus release: an electron microscope study. J Gen Virol. 1977 Feb;34(2):363–367. doi: 10.1099/0022-1317-34-2-363. [DOI] [PubMed] [Google Scholar]
  23. Chapekar M. S., Glazer R. I. Effects of fibroblast and recombinant leukocyte interferons and double-stranded RNA on ppp(2'-5')An synthesis and cell proliferation in human colon carcinoma cells in vitro. Cancer Res. 1983 Jun;43(6):2683–2687. [PubMed] [Google Scholar]
  24. Chapekar M. S., Glazer R. I. Effects of human immune interferon on cell viability, (2',5')oligoadenylate synthesis, and polyamine-dependent protein phosphorylation in human colon carcinoma cells in vitro. Cancer Res. 1984 May;44(5):2144–2149. [PubMed] [Google Scholar]
  25. Clemens M. J., McNurlan M. A., Moore G., Tilleray V. J. Regulation of protein synthesis in lymphoblastoid cells during inhibition of cell proliferation by human interferons. FEBS Lett. 1984 Jun 4;171(1):111–116. doi: 10.1016/0014-5793(84)80469-x. [DOI] [PubMed] [Google Scholar]
  26. Clemens M. J., Williams B. R. Inhibition of cell-free protein synthesis by pppA2'p5'A2'p5'A: a novel oligonucleotide synthesized by interferon-treated L cell extracts. Cell. 1978 Mar;13(3):565–572. doi: 10.1016/0092-8674(78)90329-x. [DOI] [PubMed] [Google Scholar]
  27. Colonno R. J. Accumulation of newly synthesized mRNAs in response to human fibroblast (beta) interferon. Proc Natl Acad Sci U S A. 1981 Aug;78(8):4763–4766. doi: 10.1073/pnas.78.8.4763. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. Colonno R. J., Pang R. H. Induction of unique mRNAs by human interferons. J Biol Chem. 1982 Aug 25;257(16):9234–9237. [PubMed] [Google Scholar]
  29. Crane J. L., Jr, Glasgow L. A., Kern E. R., Youngner J. S. Inhibition of murine osteogenic sarcomas by treatment with type I or type II interferon. J Natl Cancer Inst. 1978 Sep;61(3):871–874. [PubMed] [Google Scholar]
  30. Creasey A. A., Bartholomew J. C., Merigan T. C. Role of G0-G1 arrest in the inhibition of tumor cell growth by interferon. Proc Natl Acad Sci U S A. 1980 Mar;77(3):1471–1475. doi: 10.1073/pnas.77.3.1471. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. Creasey A. A., Bartholomew J. C., Merigan T. C. The importance of G0 in the site of action of interferon in the cell cycle. Exp Cell Res. 1981 Jul;134(1):155–160. doi: 10.1016/0014-4827(81)90472-9. [DOI] [PubMed] [Google Scholar]
  32. Creasey A. A., Eppstein D. A., Marsh Y. V., Khan Z., Merigan T. C. Growth regulation of melanoma cells by interferon and (2'-5')oligoadenylate synthetase. Mol Cell Biol. 1983 May;3(5):780–786. doi: 10.1128/mcb.3.5.780. [DOI] [PMC free article] [PubMed] [Google Scholar]
  33. Creissen D., Shall S. Regulation of DNA ligase activity by poly(ADP-ribose). Nature. 1982 Mar 18;296(5854):271–272. doi: 10.1038/296271a0. [DOI] [PubMed] [Google Scholar]
  34. De Benedetti A., Baglioni C. Inhibition of mRNA binding to ribosomes by localized activation of dsRNA-dependent protein kinase. Nature. 1984 Sep 6;311(5981):79–81. doi: 10.1038/311079a0. [DOI] [PubMed] [Google Scholar]
  35. Degre M., Glasgow L. A. Effect of interferon on cyclic adenosine monophosphate levels in cells. Antiviral Res. 1981 Sep;1(3):185–192. doi: 10.1016/0166-3542(81)90007-3. [DOI] [PubMed] [Google Scholar]
  36. Doetsch P. W., Suhadolnik R. J., Sawada Y., Mosca J. D., Flick M. B., Reichenbach N. L., Dang A. Q., Wu J. M., Charubala R., Pfleiderer W. Core (2'-5')oligoadenylate and the cordycepin analog: inhibitors of Epstein--Barr virus-induced transformation of human lymphocytes in the absence of interferon. Proc Natl Acad Sci U S A. 1981 Nov;78(11):6699–6703. doi: 10.1073/pnas.78.11.6699. [DOI] [PMC free article] [PubMed] [Google Scholar]
  37. Dougherty J. P., Samanta H., Farrell P. J., Lengyel P. Interferon, double-stranded RNA, and RNA degradation. Isolation of homogeneous pppA(2'p5'A)n-1 synthetase from Ehrlich ascites tumor cells. J Biol Chem. 1980 May 10;255(9):3813–3816. [PubMed] [Google Scholar]
  38. Dron M., Tovey M. G. Isolation of Daudi cells with reduced sensitivity to interferon. I. Characterization. J Gen Virol. 1983 Dec;64(Pt 12):2641–2647. doi: 10.1099/0022-1317-64-12-2641. [DOI] [PubMed] [Google Scholar]
  39. Dubois M. F., Vignal M., Le Cunff M., Chany C. Interferon inhibits transformation of mouse cells by exogenous cellular or viral genes. Nature. 1983 Jun 2;303(5916):433–435. doi: 10.1038/303433a0. [DOI] [PubMed] [Google Scholar]
  40. Einhorn S., Strander H. Is interferon tissue specific?- Effect of human leukocyte and fibroblast interferons on the growth of lymphoblastoid and osteosarcoma cell lines. J Gen Virol. 1977 Jun;35(3):573–577. doi: 10.1099/0022-1317-35-3-573. [DOI] [PubMed] [Google Scholar]
  41. Etienne-Smekens M., Vandenbussche P., Content J., Dumont J. E. (2'-5')Oligoadenylate in rat liver: modulation after partial hepatectomy. Proc Natl Acad Sci U S A. 1983 Aug;80(15):4609–4613. doi: 10.1073/pnas.80.15.4609. [DOI] [PMC free article] [PubMed] [Google Scholar]
  42. Faltynek C. R., Branca A. A., McCandless S., Baglioni C. Characterization of an interferon receptor on human lymphoblastoid cells. Proc Natl Acad Sci U S A. 1983 Jun;80(11):3269–3273. doi: 10.1073/pnas.80.11.3269. [DOI] [PMC free article] [PubMed] [Google Scholar]
  43. Farrell P. J., Broeze R. J., Lengyel P. Accumulation of an mRNA and protein in interferon-treated Ehrlich ascites tumour cells. Nature. 1979 Jun 7;279(5713):523–525. doi: 10.1038/279523a0. [DOI] [PubMed] [Google Scholar]
  44. Farrell P. J., Sen G. C., Dubois M. F., Ratner L., Slattery E., Lengyel P. Interferon action: two distinct pathways for inhibition of protein synthesis by double-stranded RNA. Proc Natl Acad Sci U S A. 1978 Dec;75(12):5893–5897. doi: 10.1073/pnas.75.12.5893. [DOI] [PMC free article] [PubMed] [Google Scholar]
  45. Fellous M., Nir U., Wallach D., Merlin G., Rubinstein M., Revel M. Interferon-dependent induction of mRNA for the major histocompatibility antigens in human fibroblasts and lymphoblastoid cells. Proc Natl Acad Sci U S A. 1982 May;79(10):3082–3086. doi: 10.1073/pnas.79.10.3082. [DOI] [PMC free article] [PubMed] [Google Scholar]
  46. Fisher P. B., Miranda A. F., Babiss L. E., Pestka S., Weinstein I. B. Opposing effects of interferon produced in bacteria and of tumor promoters on myogenesis in human myoblast cultures. Proc Natl Acad Sci U S A. 1983 May;80(10):2961–2965. doi: 10.1073/pnas.80.10.2961. [DOI] [PMC free article] [PubMed] [Google Scholar]
  47. Fisher P. B., Mufson R. A., Weinstein I. B. Interferon inhibits melanogenesis in B-16 mouse melanoma cells. Biochem Biophys Res Commun. 1981 May 29;100(2):823–830. doi: 10.1016/s0006-291x(81)80248-3. [DOI] [PubMed] [Google Scholar]
  48. Fleischmann W. R., Jr Potentiation of the direct anticellular activity of mouse interferons: mutual synergism and interferon concentration dependence. Cancer Res. 1982 Mar;42(3):869–875. [PubMed] [Google Scholar]
  49. Forti R. L., Mitchell W. M., Hubbard W. C., Workman R. J., Forbes J. T. Pleiotropic activities of human interferons are mediated by multiple response pathways. Proc Natl Acad Sci U S A. 1984 Jan;81(1):170–174. doi: 10.1073/pnas.81.1.170. [DOI] [PMC free article] [PubMed] [Google Scholar]
  50. Fuse A., Kuwata T. Effects of interferon on the human clonal cell line, RSa: inhibition of macromolecular synthesis. J Gen Virol. 1976 Oct;33(1):17–24. doi: 10.1099/0022-1317-33-1-17. [DOI] [PubMed] [Google Scholar]
  51. Fuse A., Kuwata T. Inhibition of DNA synthesis and alteration of cyclic adenosine 3',5'-monophosphate levels in RSa cells by human leukocyte interferon. J Natl Cancer Inst. 1978 Jun;60(6):1227–1232. doi: 10.1093/jnci/60.6.1227. [DOI] [PubMed] [Google Scholar]
  52. Fuse A., Kuwata T. Inhibition of DNA synthesis of synchronized RSa cells by human leukocyte interferon. J Natl Cancer Inst. 1977 Apr;58(4):891–896. doi: 10.1093/jnci/58.4.891. [DOI] [PubMed] [Google Scholar]
  53. Fuse T. K., Morinaga N. Effects of interferon on cell and virus growth in transformed human cell lines. J Gen Virol. 1976 Oct;33(1):7–15. doi: 10.1099/0022-1317-33-1-7. [DOI] [PubMed] [Google Scholar]
  54. Garlick P. J., McNurlan M. A., Preedy V. R. A rapid and convenient technique for measuring the rate of protein synthesis in tissues by injection of [3H]phenylalanine. Biochem J. 1980 Nov 15;192(2):719–723. doi: 10.1042/bj1920719. [DOI] [PMC free article] [PubMed] [Google Scholar]
  55. Gazitt Y. Inhibition of induced L-ornithine decarboxylase stimulation and erythrodifferentiation in Friend erythroleukemia cells by 2',5'-isoadenylate trimer core. Cancer Res. 1981 Jul;41(7):2959–2961. [PubMed] [Google Scholar]
  56. Gerfaux J., Rousset S., Chany-Fournier F., Chany C. Interferon effect on collagen and fibronectin distribution in the extracellular matrix of murine sarcoma virus-transformed cells. Cancer Res. 1981 Sep;41(9 Pt 1):3629–3634. [PubMed] [Google Scholar]
  57. Gewert D. R., Moore G., Clemens M. J. Inhibition of cell division by interferons. The relationship between changes in utilization of thymidine for DNA synthesis and control of proliferation in Daudi cells. Biochem J. 1983 Sep 15;214(3):983–990. doi: 10.1042/bj2140983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  58. Gewert D. R., Moore G., Tilleray V. J., Clemens M. J. Inhibition of cell proliferation by interferons. 1. Effects on cell division and DNA synthesis in human lymphoblastoid (Daudi) cells. Eur J Biochem. 1984 Mar 15;139(3):619–625. doi: 10.1111/j.1432-1033.1984.tb08049.x. [DOI] [PubMed] [Google Scholar]
  59. Gewert D. R., Shah S., Clemens M. J. Inhibition of cell division by interferons: Changes in the transport and intracellular metabolism of thymidine in human lymphoblastoid (Daudi) cells. Eur J Biochem. 1981 Jun 1;116(3):487–492. doi: 10.1111/j.1432-1033.1981.tb05362.x. [DOI] [PubMed] [Google Scholar]
  60. Gidlund M., Orn A., Wigzell H., Senik A., Gresser I. Enhanced NK cell activity in mice injected with interferon and interferon inducers. Nature. 1978 Jun 29;273(5665):759–761. doi: 10.1038/273759a0. [DOI] [PubMed] [Google Scholar]
  61. Grant S., Bhalla K., Weinstein I. B., Pestka S., Fisher P. B. Differential effect of recombinant human leukocyte interferon on human leukemic and normal myeloid progenitor cells. Biochem Biophys Res Commun. 1982 Oct 15;108(3):1048–1055. doi: 10.1016/0006-291x(82)92105-2. [DOI] [PubMed] [Google Scholar]
  62. Gresser I. Antitumor effects of interferon. Adv Cancer Res. 1972;16:97–140. doi: 10.1016/s0065-230x(08)60339-5. [DOI] [PubMed] [Google Scholar]
  63. Gresser I., Bourali C. Antitumor effects of interferon preparations in mice. J Natl Cancer Inst. 1970 Aug;45(2):365–376. [PubMed] [Google Scholar]
  64. Gresser I., Tovey M. G. Antitumor effects of interferon. Biochim Biophys Acta. 1978 Oct 27;516(2):231–247. doi: 10.1016/0304-419x(78)90009-4. [DOI] [PubMed] [Google Scholar]
  65. Gupta S. L., Rubin B. Y., Holmes S. L. Interferon action: induction of specific proteins in mouse and human cells by homologous interferons. Proc Natl Acad Sci U S A. 1979 Oct;76(10):4817–4821. doi: 10.1073/pnas.76.10.4817. [DOI] [PMC free article] [PubMed] [Google Scholar]
  66. Gupta S. L., Rubin B. Y., Holmes S. L. Regulation of interferon action in human fibroblasts: transient induction of specific proteins and amplification of the antiviral response by antinomycin D. Virology. 1981 Jun;111(2):331–340. doi: 10.1016/0042-6822(81)90337-8. [DOI] [PubMed] [Google Scholar]
  67. Gurari-Rotman D., Revel M., Tartakovsky B., Segal S., Hahn T., Handzel Z., Levin S. Lymphoblastogenesis in Down's syndrome and its inhibition by human interferon. FEBS Lett. 1978 Oct 15;94(2):187–190. doi: 10.1016/0014-5793(78)80934-x. [DOI] [PubMed] [Google Scholar]
  68. Henderson E. E., Doetsch P. W., Charubala R., Pfleiderer W., Suhadolnik R. J. Inhibition of Epstein-Barr virus-associated nuclear antigen (EBNA) induction by (2',5')oligoadenylate and the cordycepin analog: mechanism of action for inhibition of EBV-induced transformation. Virology. 1982 Oct 15;122(1):198–201. doi: 10.1016/0042-6822(82)90389-0. [DOI] [PubMed] [Google Scholar]
  69. Henshaw E. C., Hirsch C. A., Morton B. E., Hiatt H. H. Control of protein synthesis in mammalian tissues through changes in ribosome activity. J Biol Chem. 1971 Jan 25;246(2):436–446. [PubMed] [Google Scholar]
  70. Hersh C. L., Brown R. E., Roberts W. K., Swyryd E. A., Kerr I. M., Stark G. R. Simian virus 40-infected, interferon-treated cells contain 2',5'-oligoadenylates which do not activate cleavage of RNA. J Biol Chem. 1984 Feb 10;259(3):1731–1737. [PubMed] [Google Scholar]
  71. Hicks N. J., Morris A. G., Burke D. C. Partial reversion of the transformed phenotype of murine sarcoma virus-transformed cells in the presence of interferon: a possible mechanism for the anti-tumour effect of interferon. J Cell Sci. 1981 Jun;49:225–236. doi: 10.1242/jcs.49.1.225. [DOI] [PubMed] [Google Scholar]
  72. Hilfenhaus J., Damm H., Johannsen R. Sensitivity of various human lymphoblastoid cells to the antiviral and anticellular activity of human leukocyte interferon. Arch Virol. 1977;54(3):271–277. doi: 10.1007/BF01314795. [DOI] [PubMed] [Google Scholar]
  73. Hilfenhaus J., Damm H., Karges H. E., Manthey K. F. Growth inhibition of human lymphoblastoid Daudi cells in vitro by interferon preparations. Arch Virol. 1976;51(1-2):87–97. doi: 10.1007/BF01317837. [DOI] [PubMed] [Google Scholar]
  74. Hovanessian A. G. Intracellular events in interferon-treated cells. Differentiation. 1979;15(3):139–151. doi: 10.1111/j.1432-0436.1979.tb01044.x. [DOI] [PubMed] [Google Scholar]
  75. Hovanessian A. G., Kerr I. M. The (2'-5') oligoadenylate (pppA2'-5'A2'-5'A) synthetase and protein kinase(s) from interferon-treated cells. Eur J Biochem. 1979 Feb 1;93(3):515–526. doi: 10.1111/j.1432-1033.1979.tb12850.x. [DOI] [PubMed] [Google Scholar]
  76. Hovanessian A. G., La Bonnardiere C., Falcoff E. Action of murine gamma (immune)interferon on beta (fibroblast)-interferon resistant L 1210 and embryonal carcinoma cells. J Interferon Res. 1980 Fall;1(1):125–135. doi: 10.1089/jir.1980.1.125. [DOI] [PubMed] [Google Scholar]
  77. Hovanessian A. G., Wood J., Meurs E., Montagnier L. Increased nuclease activity in cells treated with pppA2'p5'A2'p5' A. Proc Natl Acad Sci U S A. 1979 Jul;76(7):3261–3265. doi: 10.1073/pnas.76.7.3261. [DOI] [PMC free article] [PubMed] [Google Scholar]
  78. Ito M., Buffett R. F. Cytocidal effect of purified human fibroblast interferon on tumor cells in vitro. J Natl Cancer Inst. 1981 May;66(5):819–825. [PubMed] [Google Scholar]
  79. Iwakura Y., Yonehara S., Kawade Y. Purification of mouse L cell interferon. Essentially pure preparations with associated cell growth inhibitory activity. J Biol Chem. 1978 Jul 25;253(14):5074–5079. [PubMed] [Google Scholar]
  80. Jacobsen H., Krause D., Friedman R. M., Silverman R. H. Induction of ppp(A2'p)nA-dependent RNase in murine JLS-V9R cells during growth inhibition. Proc Natl Acad Sci U S A. 1983 Aug;80(16):4954–4958. doi: 10.1073/pnas.80.16.4954. [DOI] [PMC free article] [PubMed] [Google Scholar]
  81. Jonak G. J., Knight E., Jr Selective reduction of c-myc mRNA in Daudi cells by human beta interferon. Proc Natl Acad Sci U S A. 1984 Mar;81(6):1747–1750. doi: 10.1073/pnas.81.6.1747. [DOI] [PMC free article] [PubMed] [Google Scholar]
  82. Keay S., Grossberg S. E. Interferon inhibits the conversion of 3T3-L1 mouse fibroblasts into adipocytes. Proc Natl Acad Sci U S A. 1980 Jul;77(7):4099–4103. doi: 10.1073/pnas.77.7.4099. [DOI] [PMC free article] [PubMed] [Google Scholar]
  83. Kelly K., Cochran B. H., Stiles C. D., Leder P. Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor. Cell. 1983 Dec;35(3 Pt 2):603–610. doi: 10.1016/0092-8674(83)90092-2. [DOI] [PubMed] [Google Scholar]
  84. Kerr I. M., Brown R. E. pppA2'p5'A2'p5'A: an inhibitor of protein synthesis synthesized with an enzyme fraction from interferon-treated cells. Proc Natl Acad Sci U S A. 1978 Jan;75(1):256–260. doi: 10.1073/pnas.75.1.256. [DOI] [PMC free article] [PubMed] [Google Scholar]
  85. Kimchi A. Increased levels of interferon-induced (2'--5') oligo-isoadenylate synthetase in mature T-lymphocytes and in differentiated Friend-erythroleukemic cells. J Interferon Res. 1981;1(4):559–569. doi: 10.1089/jir.1981.1.559. [DOI] [PubMed] [Google Scholar]
  86. Kimchi A., Shulman L., Schmidt A., Chernajovsky Y., Fradin A., Revel M. Kinetics of the induction of three translation-regulatory enzymes by interferon. Proc Natl Acad Sci U S A. 1979 Jul;76(7):3208–3212. doi: 10.1073/pnas.76.7.3208. [DOI] [PMC free article] [PubMed] [Google Scholar]
  87. Kimchi A., Shure H., Lapidot Y., Rapoport S., Panet A., Revel M. Antimitogenic effects of interferon and (2'-5')-oligoadenylate in synchronized 3T3 fibroblasts. FEBS Lett. 1981 Nov 16;134(2):212–216. doi: 10.1016/0014-5793(81)80604-7. [DOI] [PubMed] [Google Scholar]
  88. Kimchi A., Shure H., Revel M. Anti-mitogenic function of interferon-induced (2'-5')oligo(adenylate) and growth-related variations in enzymes that synthesize and degrade this oligonucleotide. Eur J Biochem. 1981;114(1):5–10. doi: 10.1111/j.1432-1033.1981.tb06163.x. [DOI] [PubMed] [Google Scholar]
  89. Kimchi A., Shure H., Revel M. Regulation of lymphocyte mitogenesis by (2'--5') oligo-isoadenylate. Nature. 1979 Dec 20;282(5741):849–851. doi: 10.1038/282849a0. [DOI] [PubMed] [Google Scholar]
  90. Kimchi A., Zilberstein A., Schmidt A., Shulman L., Revel M. The interferon-induced protein kinase PK-i from mouse L cells. J Biol Chem. 1979 Oct 10;254(19):9846–9853. [PubMed] [Google Scholar]
  91. Knight E., Jr Antiviral and cell growth inhibitory activities reside in the same glycoprotein of human fibroblast interferon. Nature. 1976 Jul 22;262(5566):302–303. doi: 10.1038/262302a0. [DOI] [PubMed] [Google Scholar]
  92. Knight E., Jr, Korant B. D. Fibroblast interferon induces synthesis of four proteins in human fibroblast cells. Proc Natl Acad Sci U S A. 1979 Apr;76(4):1824–1827. doi: 10.1073/pnas.76.4.1824. [DOI] [PMC free article] [PubMed] [Google Scholar]
  93. Krishnan I., Baglioni C. Elevated levels of (2'-5')oligoadenylic acid polymerase activity in growth-arrested human lymphoblastoid Namalva cells. Mol Cell Biol. 1981 Oct;1(10):932–938. doi: 10.1128/mcb.1.10.932. [DOI] [PMC free article] [PubMed] [Google Scholar]
  94. Krishnan I., Baglioni C. Increased levels of (2'-5')oligo(A) polymerase activity in human lymphoblastoid cells treated with glucocorticoids. Proc Natl Acad Sci U S A. 1980 Nov;77(11):6506–6510. doi: 10.1073/pnas.77.11.6506. [DOI] [PMC free article] [PubMed] [Google Scholar]
  95. Leanderson T., Lundgren E. Growth inhibition by IFN achieved by collecting cells in G0. J Interferon Res. 1982;2(1):21–29. doi: 10.1089/jir.1982.2.21. [DOI] [PubMed] [Google Scholar]
  96. Leanderson T., Nordfelth R., Lundgren E. Antiproliferative effect of (2'-5') oligoadenylate distinct from that of interferon in lymphoid cells. Biochem Biophys Res Commun. 1982 Jul 30;107(2):511–517. doi: 10.1016/0006-291x(82)91521-2. [DOI] [PubMed] [Google Scholar]
  97. Lee S. H., Kelley S., Chiu H., Stebbing N. Stimulation of natural killer cell activity and inhibition of proliferation of various leukemic cells by purified human leukocyte interferon subtypes. Cancer Res. 1982 Apr;42(4):1312–1316. [PubMed] [Google Scholar]
  98. Leibson H. J., Gefter M., Zlotnik A., Marrack P., Kappler J. W. Role of gamma-interferon in antibody-producing responses. 1984 Jun 28-Jul 4Nature. 309(5971):799–801. doi: 10.1038/309799a0. [DOI] [PubMed] [Google Scholar]
  99. Lengyel P. Biochemistry of interferons and their actions. Annu Rev Biochem. 1982;51:251–282. doi: 10.1146/annurev.bi.51.070182.001343. [DOI] [PubMed] [Google Scholar]
  100. Lewis J. A., Esteban M. Induction of an anti-viral response and 2',5'-oligo A synthetase by interferon in several thymidine kinase-deficient cell lines. Virology. 1984 Mar;133(2):464–469. doi: 10.1016/0042-6822(84)90415-x. [DOI] [PubMed] [Google Scholar]
  101. Lewis J. A., Mengheri E., Esteban M. Induction of an antiviral response by interferon requires thymidine kinase. Proc Natl Acad Sci U S A. 1983 Jan;80(1):26–30. doi: 10.1073/pnas.80.1.26. [DOI] [PMC free article] [PubMed] [Google Scholar]
  102. Lieberman D., Voloch Z., Aviv H., Nudel U., Revel M. Effects of interferon on hemoglobin synthesis and leukemia virus production in Friend cells. Mol Biol Rep. 1974 Dec;1(8):447–451. doi: 10.1007/BF00360670. [DOI] [PubMed] [Google Scholar]
  103. Lin J. C., Smith M. C., Pagano J. S. Effects of 12-O-tetradecanoyl-phorbol-13-acetate on cell proliferation and Epstein-Barr virus DNA replication. Virology. 1982 Feb;117(1):186–194. doi: 10.1016/0042-6822(82)90518-9. [DOI] [PubMed] [Google Scholar]
  104. Lin S. L., Garber E. A., Wang E., Caliguiri L. A., Schellekens H., Goldberg A. R., Tamm I. Reduced synthesis of pp60src and expression of the transformation-related phenotype in interferon-treated Rous sarcoma virus-transformed rat cells. Mol Cell Biol. 1983 Sep;3(9):1656–1664. doi: 10.1128/mcb.3.9.1656. [DOI] [PMC free article] [PubMed] [Google Scholar]
  105. Lin S. L., Ts'o P. O., Hollenberg M. D. The effects of interferon on epidermal growth factor action. Biochem Biophys Res Commun. 1980 Sep 16;96(1):168–174. doi: 10.1016/0006-291x(80)91196-1. [DOI] [PubMed] [Google Scholar]
  106. Lindahl-Magnusson P., Leary P., Gresser I. Interferon inhibits DNA synthesis induced in mouse lymphocyte suspensions by phytohaemagglutinin or by allogeneic cells. Nat New Biol. 1972 May 24;237(73):120–121. doi: 10.1038/newbio237120a0. [DOI] [PubMed] [Google Scholar]
  107. Lindahl P., Gresser I., Leary P., Tovey M. Interferon treatment of mice: enhanced expression of histocompatibility antigens on lymphoid cells. Proc Natl Acad Sci U S A. 1976 Apr;73(4):1284–1287. doi: 10.1073/pnas.73.4.1284. [DOI] [PMC free article] [PubMed] [Google Scholar]
  108. Lough J., Keay S., Sabran J. L., Grossberg S. E. Inhibition of chicken myogenesis in vitro by partially purified interferon. Biochem Biophys Res Commun. 1982 Nov 16;109(1):92–99. doi: 10.1016/0006-291x(82)91570-4. [DOI] [PubMed] [Google Scholar]
  109. Lundblad D., Lundgren E. Block of glioma cell line in S by interferon. Int J Cancer. 1981 Jun 15;27(6):749–754. doi: 10.1002/ijc.2910270604. [DOI] [PubMed] [Google Scholar]
  110. Lundblad D., Lundgren E. Changes in DNA-polymerase and thymidine kinase activity during interferon treatment. Biochem Biophys Res Commun. 1982 Apr 29;105(4):1569–1576. doi: 10.1016/0006-291x(82)90967-6. [DOI] [PubMed] [Google Scholar]
  111. Lundgren E., Larsson I., Miörner H., Strannegård O. Effects of leukocyte and fibroblast interferon on events in the fibroblast cell cycle. J Gen Virol. 1979 Mar;42(3):589–595. doi: 10.1099/0022-1317-42-3-589. [DOI] [PubMed] [Google Scholar]
  112. Mallucci L., Rasbridge S., Wells V. Cell cycle study on the effect of interferon on synchronized mouse embryo fibroblasts. J Interferon Res. 1983;3(2):181–189. doi: 10.1089/jir.1983.3.181. [DOI] [PubMed] [Google Scholar]
  113. Martin E. M., Reisinger D. M., Hovanessian A. G., Williams B. R. Procedures for the assay of (2'-5')-oligoadenylic acids and their derivatives in intact cells. Methods Enzymol. 1981;79(Pt B):273–284. doi: 10.1016/s0076-6879(81)79039-6. [DOI] [PubMed] [Google Scholar]
  114. Matarese G. P., Rossi G. B. Effect of interferon on growth and division cycle of Friend erythroleukemic murine cells in vitro. J Cell Biol. 1977 Nov;75(2 Pt 1):344–354. doi: 10.1083/jcb.75.2.344. [DOI] [PMC free article] [PubMed] [Google Scholar]
  115. Matsuno T., Shirasawa N. Interferon suppresses steroid-inducible glutamine synthetase biosynthesis in embryonic chick neural retina. Biochim Biophys Acta. 1978 Jan 18;538(2):188–194. doi: 10.1016/0304-4165(78)90345-8. [DOI] [PubMed] [Google Scholar]
  116. Menezes J., Patel P., Dussault H., Joncas J., Leibold W. Effect of interferon on lymphocyte transformation and nuclear antigen production by Epstein-Barr virus. Nature. 1976 Apr 1;260(5550):430–432. doi: 10.1038/260430a0. [DOI] [PubMed] [Google Scholar]
  117. Mengheri E., Esteban M., Lewis J. A. Thymidine kinase genes and the induction of anti-viral responses by interferon. FEBS Lett. 1983 Jul 4;157(2):301–305. doi: 10.1016/0014-5793(83)80565-1. [DOI] [PubMed] [Google Scholar]
  118. Metz D. H., Levin M. J., Oxman M. N. Mechanism of interferon action: further evidence for transcription as the primary site of action in simian virus 40 infection. J Gen Virol. 1976 Aug;32(2):227–240. doi: 10.1099/0022-1317-32-2-227. [DOI] [PubMed] [Google Scholar]
  119. Mogensen K. E., Bandu M. T. Kinetic evidence for an activation step following binding of human interferon alpha 2 to the membrane receptors of Daudi cells. Eur J Biochem. 1983 Aug 1;134(2):355–364. doi: 10.1111/j.1432-1033.1983.tb07575.x. [DOI] [PubMed] [Google Scholar]
  120. Moore G., Gewert D. R., Clemens M. J. Inhibition of cell proliferation by interferons. 2. Changes in processing and stability of newly synthesized DNA in human lymphoblastoid (Daudi) cells. Eur J Biochem. 1984 Mar 15;139(3):627–635. doi: 10.1111/j.1432-1033.1984.tb08050.x. [DOI] [PubMed] [Google Scholar]
  121. Nakamura M., Manser T., Pearson G. D., Daley M. J., Gefter M. L. Effect of IFN-gamma on the immune response in vivo and on gene expression in vitro. 1984 Jan 26-Feb 1Nature. 307(5949):381–382. doi: 10.1038/307381a0. [DOI] [PubMed] [Google Scholar]
  122. Nebert D. W., Friedman R. M. Stimulation of aryl hydrocarbon hydroxylase induction in cell cultures by interferon. J Virol. 1973 Feb;11(2):193–197. doi: 10.1128/jvi.11.2.193-197.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  123. Nilsen T. W., Baglioni C. Mechanism for discrimination between viral and host mRNA in interferon-treated cells. Proc Natl Acad Sci U S A. 1979 Jun;76(6):2600–2604. doi: 10.1073/pnas.76.6.2600. [DOI] [PMC free article] [PubMed] [Google Scholar]
  124. Nilsen T. W., Wood D. L., Baglioni C. Presence of 2',5'-oligo(A) and of enzymes that synthesize, bind, and degrade 2',5'-oligo(A) in HeLa cell nuclei. J Biol Chem. 1982 Feb 25;257(4):1602–1605. [PubMed] [Google Scholar]
  125. Ohtsuki K., Baron S. An interferon-induced, ribosome-associated protein kinase which reduces the activity of initiation factor. J Biochem. 1979 Jun;85(6):1495–1502. doi: 10.1093/oxfordjournals.jbchem.a132478. [DOI] [PubMed] [Google Scholar]
  126. Otsuka H., Qavi H., Kit S. Inhibition by interferon of biochemical transformation induced by cloned herpesvirus thymidine kinase genes. Antiviral Res. 1982 Oct;2(5):301–311. doi: 10.1016/0166-3542(82)90053-5. [DOI] [PubMed] [Google Scholar]
  127. Oxman M. N., Baron S., Black P. H., Takemoto K. K., Habel K., Rowe W. P. The effect of interferon on SV-40 T antigen production in SV-40-transformed cells. Virology. 1967 May;32(1):122–127. doi: 10.1016/0042-6822(67)90260-7. [DOI] [PubMed] [Google Scholar]
  128. PAUCKER K., CANTELL K., HENLE W. Quantitative studies on viral interference in suspended L cells. III. Effect of interfering viruses and interferon on the growth rate of cells. Virology. 1962 Jun;17:324–334. doi: 10.1016/0042-6822(62)90123-x. [DOI] [PubMed] [Google Scholar]
  129. Pain V. M., Clemens M. J. Assembly and breakdown of mammalian protein synthesis initiation complexes: regulation by guanine nucleotides and by phosphorylation of initiation factor eIF-2. Biochemistry. 1983 Feb 15;22(4):726–733. doi: 10.1021/bi00273a003. [DOI] [PubMed] [Google Scholar]
  130. Pfeffer L. M., Murphy J. S., Tamm I. Interferon effects on the growth and division of human fibroblasts. Exp Cell Res. 1979 Jun;121(1):111–120. doi: 10.1016/0014-4827(79)90450-6. [DOI] [PubMed] [Google Scholar]
  131. Pfeffer L. M., Tamm I. Comparison of the effects of alpha and beta interferons on the proliferation and volume of human tumor cells (HeLa-S3, Daudi, P3HR-1). J Interferon Res. 1983;3(4):395–408. doi: 10.1089/jir.1983.3.395. [DOI] [PubMed] [Google Scholar]
  132. Pfeffer L. M., Wang E., Tamm I. Interferon effects on microfilament organization, cellular fibronectin distribution, and cell motility in human fibroblasts. J Cell Biol. 1980 Apr;85(1):9–17. doi: 10.1083/jcb.85.1.9. [DOI] [PMC free article] [PubMed] [Google Scholar]
  133. Priestman T. J. Interferons and cancer therapy. J Pathol. 1983 Nov;141(3):287–295. doi: 10.1002/path.1711410308. [DOI] [PubMed] [Google Scholar]
  134. Quesada J. R., Reuben J., Manning J. T., Hersh E. M., Gutterman J. U. Alpha interferon for induction of remission in hairy-cell leukemia. N Engl J Med. 1984 Jan 5;310(1):15–18. doi: 10.1056/NEJM198401053100104. [DOI] [PubMed] [Google Scholar]
  135. Rehberg E., Kelder B., Hoal E. G., Pestka S. Specific molecular activities of recombinant and hybrid leukocyte interferons. J Biol Chem. 1982 Oct 10;257(19):11497–11502. [PubMed] [Google Scholar]
  136. Revel M. F., Kimchi A. Initial characterization of a spontaneous interferon secreted during growth and differentiation of Friend erythroleukemia cells. Mol Cell Biol. 1982 Dec;2(12):1472–1480. doi: 10.1128/mcb.2.12.1472. [DOI] [PMC free article] [PubMed] [Google Scholar]
  137. Rochette-Egly C., Tovey M. G. Interferon enhances guanylate cyclase activity in human lymphoma cells. Biochem Biophys Res Commun. 1982 Jul 16;107(1):150–156. doi: 10.1016/0006-291x(82)91682-5. [DOI] [PubMed] [Google Scholar]
  138. Rosa F., Berissi H., Weissenbach J., Maroteaux L., Fellous M., Revel M. The beta2-microglobulin mRNA in human Daudi cells has a mutated initiation codon but is still inducible by interferon. EMBO J. 1983;2(2):239–243. doi: 10.1002/j.1460-2075.1983.tb01412.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  139. Rosa F., Hatat D., Abadie A., Wallach D., Revel M., Fellous M. Differential regulation of HLA-DR mRNAs and cell surface antigens by interferon. EMBO J. 1983;2(9):1585–1589. doi: 10.1002/j.1460-2075.1983.tb01628.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  140. Rossi G. B., Dolei A., Cioé L., Benedetto A., Matarese G. P., Belardelli F. Inhibition of transcription and translation of globin messenger RNA in dimethyl sulfoxide-stimulated Friend erythroleukemic cells treated with interferon. Proc Natl Acad Sci U S A. 1977 May;74(5):2036–2040. doi: 10.1073/pnas.74.5.2036. [DOI] [PMC free article] [PubMed] [Google Scholar]
  141. Rossi G. B., Matarese G. P., Grappelli C., Belardelli F., Benedetto A. Interferon inhibits dimethyl sulphoxide-induced erythroid differentiation of Friend leukaemia cells. Nature. 1977 May 5;267(5606):50–52. doi: 10.1038/267050a0. [DOI] [PubMed] [Google Scholar]
  142. Rubin B. Y., Gupta S. L. Differential efficacies of human type I and type II interferons as antiviral and antiproliferative agents. Proc Natl Acad Sci U S A. 1980 Oct;77(10):5928–5932. doi: 10.1073/pnas.77.10.5928. [DOI] [PMC free article] [PubMed] [Google Scholar]
  143. Rubin B. Y., Gupta S. L. Interferon-induced proteins in human fibroblasts and development of the antiviral state. J Virol. 1980 May;34(2):446–454. doi: 10.1128/jvi.34.2.446-454.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  144. Saksela E., Timonen T., Cantell K. Human natural killer cell activity is augmented by interferon via recruitment of 'pre-NK' cells. Scand J Immunol. 1979;10(3):257–266. doi: 10.1111/j.1365-3083.1979.tb01348.x. [DOI] [PubMed] [Google Scholar]
  145. Samid D., Chang E. H., Friedman R. M. Biochemical correlates of phenotypic reversion in interferon-treated mouse cells transformed by a human oncogene. Biochem Biophys Res Commun. 1984 Feb 29;119(1):21–28. doi: 10.1016/0006-291x(84)91612-7. [DOI] [PubMed] [Google Scholar]
  146. Samuel C. E. Mechanism of interferon action: phosphorylation of protein synthesis initiation factor eIF-2 in interferon-treated human cells by a ribosome-associated kinase processing site specificity similar to hemin-regulated rabbit reticulocyte kinase. Proc Natl Acad Sci U S A. 1979 Feb;76(2):600–604. doi: 10.1073/pnas.76.2.600. [DOI] [PMC free article] [PubMed] [Google Scholar]
  147. Scher B. M., Scher W., Robinson A., Waxman S. DNA ligase and DNase activities in mouse erythroleukemia cells during dimethyl sulfoxide-induced differentiation. Cancer Res. 1982 Apr;42(4):1300–1306. [PubMed] [Google Scholar]
  148. Schmidt A., Chernajovsky Y., Shulman L., Federman P., Berissi H., Revel M. An interferon-induced phosphodiesterase degrading (2'-5') oligoisoadenylate and the C-C-A terminus of tRNA. Proc Natl Acad Sci U S A. 1979 Oct;76(10):4788–4792. doi: 10.1073/pnas.76.10.4788. [DOI] [PMC free article] [PubMed] [Google Scholar]
  149. Schmidt A., Hattori T., Hoffman T. Differentiation of a human monocyte-like cell line by (2'-5') oligoisoadenylate. Exp Cell Res. 1984 Feb;150(2):292–297. doi: 10.1016/0014-4827(84)90571-8. [DOI] [PubMed] [Google Scholar]
  150. Schneck J., Rager-Zisman B., Rosen O. M., Bloom B. R. Genetic analysis of the role of cAMP in mediating effects of interferon. Proc Natl Acad Sci U S A. 1982 Mar;79(6):1879–1883. doi: 10.1073/pnas.79.6.1879. [DOI] [PMC free article] [PubMed] [Google Scholar]
  151. Sen G. C. Mechanism of interferon action: progress toward its understanding. Prog Nucleic Acid Res Mol Biol. 1982;27:105–156. doi: 10.1016/s0079-6603(08)60599-1. [DOI] [PubMed] [Google Scholar]
  152. Sen G. C., Shaila S., Lebleu B., Brown G. E., Desrosiers R. C., Lengyel P. Impairment of reovirus mRNA methylation in extracts of interferon-treated Ehrilich ascites tumor cells: further characteristics of the phenomenon. J Virol. 1977 Jan;21(1):69–83. doi: 10.1128/jvi.21.1.69-83.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  153. Sen G. C., Taira H., Lengyel P. Interferon, double-stranded RNA, and protein phosphorylation. Characteristics of a double-stranded RNA-activated protein kinase system partially purified from interferon treated Ehrlich ascites tumor cells. J Biol Chem. 1978 Sep 10;253(17):5915–5921. [PubMed] [Google Scholar]
  154. Shibata H., Taylor-Papadimitriou J. Effects of human lymphoblastoid interferon on cultured breast cancer cells. Int J Cancer. 1981 Oct 15;28(4):447–453. doi: 10.1002/ijc.2910280409. [DOI] [PubMed] [Google Scholar]
  155. Shulman L., Revel M. Interferon-dependent induction of mRNA activity for (2'-5')oligo-isoadenylate synthetase. Nature. 1980 Nov 6;288(5786):98–100. doi: 10.1038/288098a0. [DOI] [PubMed] [Google Scholar]
  156. Siekierka J., Manne V., Ochoa S. Mechanism of translational control by partial phosphorylation of the alpha subunit of eukaryotic initiation factor 2. Proc Natl Acad Sci U S A. 1984 Jan;81(2):352–356. doi: 10.1073/pnas.81.2.352. [DOI] [PMC free article] [PubMed] [Google Scholar]
  157. Siekierka J., Mauser L., Ochoa S. Mechanism of polypeptide chain initiation in eukaryotes and its control by phosphorylation of the alpha subunit of initiation factor 2. Proc Natl Acad Sci U S A. 1982 Apr;79(8):2537–2540. doi: 10.1073/pnas.79.8.2537. [DOI] [PMC free article] [PubMed] [Google Scholar]
  158. Silverman R. H., Watling D., Balkwill F. R., Trowsdale J., Kerr I. M. The ppp(A2'p)nA and protein kinase systems in wild-type and interferon-resistant Daudi cells. Eur J Biochem. 1982 Aug;126(2):333–341. doi: 10.1111/j.1432-1033.1982.tb06783.x. [DOI] [PubMed] [Google Scholar]
  159. Slattery E., Ghosh N., Samanta H., Lengyel P. Interferon, double-stranded RNA, and RNA degradation: activation of an endonuclease by (2'-5')An. Proc Natl Acad Sci U S A. 1979 Oct;76(10):4778–4782. doi: 10.1073/pnas.76.10.4778. [DOI] [PMC free article] [PubMed] [Google Scholar]
  160. Smekens-Etienne M., Goldstein J., Ooms H. A., Dumont J. E. Variation of (2'-5')oligo(adenylate) synthetase activity during rat-liver regeneration. Eur J Biochem. 1983 Feb 1;130(2):269–273. doi: 10.1111/j.1432-1033.1983.tb07146.x. [DOI] [PubMed] [Google Scholar]
  161. Sokawa Y., Watanabe Y., Watanabe Y., Kawade Y. Interferon suppresses the transition of quiescent 3T3 cells to a growing state. Nature. 1977 Jul 21;268(5617):236–238. doi: 10.1038/268236a0. [DOI] [PubMed] [Google Scholar]
  162. Soslau G., Bogucki A. R., Gillespie D., Hubbell H. R. Phosphoproteins altered by antiproliferative doses of human interferon- beta in a human bladder carcinoma cell line. Biochem Biophys Res Commun. 1984 Mar 30;119(3):941–948. doi: 10.1016/0006-291x(84)90864-7. [DOI] [PubMed] [Google Scholar]
  163. Sreevalsan T., Taylor-Papadimitriou J., Rozengurt E. Selective inhibition by interferon of serum-stimulated biochemical events in 3T3 cells. Biochem Biophys Res Commun. 1979 Apr 13;87(3):679–685. doi: 10.1016/0006-291x(79)92012-6. [DOI] [PubMed] [Google Scholar]
  164. St Laurent G., Yoshie O., Floyd-Smith G., Samanta H., Sehgal P. B., Lengyel P. Interferon action: two (2'-5')(A)n synthetases specified by distinct mRNAs in Ehrlich ascites tumor cells treated with interferon. Cell. 1983 May;33(1):95–102. doi: 10.1016/0092-8674(83)90338-0. [DOI] [PubMed] [Google Scholar]
  165. Stark G. R., Dower W. J., Schimke R. T., Brown R. E., Kerr I. M. 2-5A synthetase: assay, distribution and variation with growth or hormone status. Nature. 1979 Mar 29;278(5703):471–473. doi: 10.1038/278471a0. [DOI] [PubMed] [Google Scholar]
  166. Suhadolnik R. J., Sawada Y., Gabriel J., Reichenbach N. L., Henderson E. E. Accumulation of low molecular weight DNA and changes in chromatin structure in HeLa cells treated with human fibroblast interferon. J Biol Chem. 1984 Apr 25;259(8):4764–4769. [PubMed] [Google Scholar]
  167. Sundström S., Ny T., Lundgren E. Growth-state independent induction of specific proteins in Swiss 3T3 cells by interferon. J Interferon Res. 1983;3(2):223–229. doi: 10.1089/jir.1983.3.223. [DOI] [PubMed] [Google Scholar]
  168. Taylor-Papadimitriou J., Shearer M., Balkwill F. R., Fantes K. H. Effects of HuIFN-alpha 2 and HuIFN-alpha (Namalwa) on breast cancer cells grown in culture and as xenografts in the nude mouse. J Interferon Res. 1982;2(4):479–491. doi: 10.1089/jir.1982.2.479. [DOI] [PubMed] [Google Scholar]
  169. Taylor-Papadimitriou J., Shearer M., Rozengurt E. Inhibitory effect of interferon on cellular DNA synthesis: modulation by pure mitogenic factors. J Interferon Res. 1981;1(3):401–409. doi: 10.1089/jir.1981.1.401. [DOI] [PubMed] [Google Scholar]
  170. Terada M., Nudel U., Fibach E., Rifkind R. A., Marks P. A. Changes in DNA associated with induction of erythroid differentiation by dimethyl sulfoxide in murine erythroleukemia cells. Cancer Res. 1978 Mar;38(3):835–840. [PubMed] [Google Scholar]
  171. Tomida M., Yamamoto Y., Hozumi M. Stimulation by interferon of induction of differentiation of human promyelocytic leukemia cells. Biochem Biophys Res Commun. 1982 Jan 15;104(1):30–37. doi: 10.1016/0006-291x(82)91936-2. [DOI] [PubMed] [Google Scholar]
  172. Tomida M., Yamamoto Y., Hozumi M. Stimulation by interferon of induction of differentiation of mouse myeloid leukemic cells. Cancer Res. 1980 Aug;40(8 Pt 1):2919–2924. [PubMed] [Google Scholar]
  173. Tomita Y., Cantell K., Kuwata T. Effects of human gamma interferon on cell growth, replication of virus and induction of 2'-5'oligoadenylate synthetase in three human lymphoblastoid cell lines and K562 cells. Int J Cancer. 1982 Aug 15;30(2):161–165. doi: 10.1002/ijc.2910300206. [DOI] [PubMed] [Google Scholar]
  174. Tovey M. G., Dron M., Gresser I. Interferon enhances the expression of epstein-Barr virus early antigen in Daudi cells. J Gen Virol. 1982 May;60(Pt 1):31–38. doi: 10.1099/0022-1317-60-1-31. [DOI] [PubMed] [Google Scholar]
  175. Tovey M. G., Dron M., Mogensen K. E., Lebleu B., Mechti N., Begonlours-Guymarho J. Isolation of Daudi cells with reduced sensitivity to interferon. II. On the mechanisms of resistance. J Gen Virol. 1983 Dec;64(Pt 12):2649–2653. doi: 10.1099/0022-1317-64-12-2649. [DOI] [PubMed] [Google Scholar]
  176. Tovey M. G., Rochette-Egly C. Rapid increase in guanosine 3',5'-cyclic-monophosphate interferon treated mouse leukemia L1210 cells: relationship to the development of the antiviral state and inhibition of cell multiplication. Virology. 1981 Dec;115(2):272–281. doi: 10.1016/0042-6822(81)90110-0. [DOI] [PubMed] [Google Scholar]
  177. Tovey M., Brouty-Boyé D., Gresser I. Early effect of interferon on mouse leukemia cells cultivated in a chemostat. Proc Natl Acad Sci U S A. 1975 Jun;72(6):2265–2269. doi: 10.1073/pnas.72.6.2265. [DOI] [PMC free article] [PubMed] [Google Scholar]
  178. Turek L. P., Byrne J. C., Lowy D. R., Dvoretzky I., Friedman R. M., Howley P. M. Interferon induces morphologic reversion with elimination of extrachromosomal viral genomes in bovine papillomavirus-transformed mouse cells. Proc Natl Acad Sci U S A. 1982 Dec;79(24):7914–7918. doi: 10.1073/pnas.79.24.7914. [DOI] [PMC free article] [PubMed] [Google Scholar]
  179. Vandenbussche P., Divizia M., Verhaegen-Lewalle M., Fuse A., Kuwata T., De Clercq E., Content J. Enzymatic activities induced by interferon in human fibroblast cell lines differing in their sensitivity to the anticellular activity of interferon. Virology. 1981 May;111(1):11–22. doi: 10.1016/0042-6822(81)90649-8. [DOI] [PubMed] [Google Scholar]
  180. Verhaegen-Lewalle M., Kuwata T., Zhang Z. X., DeClercq E., Cantell K., Content J. 2-5A synthetase activity induced by interferon alpha, beta, and gamma in human cell lines differing in their sensitivity to the anticellular and antiviral activities of these interferons. Virology. 1982 Mar;117(2):425–434. doi: 10.1016/0042-6822(82)90481-0. [DOI] [PubMed] [Google Scholar]
  181. Verhaegen M., Divizia M., Vandenbussche P., Kuwata T., Content J. Abnormal behavior of interferon-induced enzymatic activities in an interferon-resistant cell line. Proc Natl Acad Sci U S A. 1980 Aug;77(8):4479–4483. doi: 10.1073/pnas.77.8.4479. [DOI] [PMC free article] [PubMed] [Google Scholar]
  182. Wang E., Pfeffer L. M., Tamm I. Interferon increases the abundance of submembranous microfilaments in HeLa-S3 cells in suspension culture. Proc Natl Acad Sci U S A. 1981 Oct;78(10):6281–6285. doi: 10.1073/pnas.78.10.6281. [DOI] [PMC free article] [PubMed] [Google Scholar]
  183. Weil J., Epstein C. J., Epstein L. B., Sedmak J. J., Sabran J. L., Grossberg S. E. A unique set of polypeptides is induced by gamma interferon in addition to those induced in common with alpha and beta interferons. Nature. 1983 Feb 3;301(5899):437–439. doi: 10.1038/301437a0. [DOI] [PubMed] [Google Scholar]
  184. Weinstein Y., Brodeur B. R., Melmon K. L., Merigan T. C. Interferon inhibition of lymphocyte mitogenesis. Immunology. 1977 Sep;33(3):313–319. [PMC free article] [PubMed] [Google Scholar]
  185. West D. K., Baglioni C. Induction of interferon in HeLa cells of a protein kinase activated by double-stranded RNA. Eur J Biochem. 1979 Nov;101(2):461–468. doi: 10.1111/j.1432-1033.1979.tb19740.x. [DOI] [PubMed] [Google Scholar]
  186. Williams B. R., Golgher R. R., Kerr I. M. Activation of a nuclease by pppA2'p5'A2'p5'A in intact cells. FEBS Lett. 1979 Sep 1;105(1):47–52. doi: 10.1016/0014-5793(79)80885-6. [DOI] [PubMed] [Google Scholar]
  187. Wreschner D. H., James T. C., Silverman R. H., Kerr I. M. Ribosomal RNA cleavage, nuclease activation and 2-5A(ppp(A2'p)nA) in interferon-treated cells. Nucleic Acids Res. 1981 Apr 10;9(7):1571–1581. doi: 10.1093/nar/9.7.1571. [DOI] [PMC free article] [PubMed] [Google Scholar]
  188. Yakobson E., Prives C., Hartman J. R., Winocour E., Revel M. Inhibition of viral protein synthesis in monkey cells treated with interferon late in simian virus 40 lytic cycle. Cell. 1977 Sep;12(1):73–81. doi: 10.1016/0092-8674(77)90186-6. [DOI] [PubMed] [Google Scholar]
  189. Yamamoto K., Yamaguchi N., Oda K. Mechanism of interferon-induced inhibition of early simian virus 40(SV40) functions. Virology. 1975 Nov;68(1):58–70. doi: 10.1016/0042-6822(75)90147-6. [DOI] [PubMed] [Google Scholar]
  190. Yaron M., Yaron I., Gurari-Rotman D., Revel M., Lindner H. R., Zor U. Stimulation of prostaglandin E production in cultured human fibroblasts by poly(I)-poly(C) and human interferon. Nature. 1977 Jun 2;267(5610):457–459. doi: 10.1038/267457a0. [DOI] [PubMed] [Google Scholar]
  191. Zeng Y., Zhong J. M., de Thé G., Wu S. H., Hou Y. T., Miao X. Q. Enhancement of spontaneous VCA and EA induction in B95-8 cells and EA induction in Raji cells treated with human leukocyte interferon. Intervirology. 1982;18(1-2):33–37. doi: 10.1159/000149301. [DOI] [PubMed] [Google Scholar]
  192. Zilberstein A., Dudock B., Berissi H., Revel M. Control of messenger RNA translation by minor species of leucyl-transfer RNA in extracts from interferon-treated L cells. J Mol Biol. 1976 Nov;108(1):43–54. doi: 10.1016/s0022-2836(76)80093-9. [DOI] [PubMed] [Google Scholar]
  193. de Ferra F., Baglioni C. Increase in S-adenosylhomocysteine concentration in interferon-treated HeLa cells and inhibition of methylation of vesicular stomatitis virus mRNA. J Biol Chem. 1983 Feb 25;258(4):2118–2121. [PubMed] [Google Scholar]
  194. zur Hausen H., Bornkamm G. W., Schmidt R., Hecker E. Tumor initiators and promoters in the induction of Epstein-Barr virus. Proc Natl Acad Sci U S A. 1979 Feb;76(2):782–785. doi: 10.1073/pnas.76.2.782. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Biochemical Journal are provided here courtesy of The Biochemical Society

RESOURCES