Figure 3.

ctDNA status and disease progression. The presence of ctDNA in pre- and post-operative plasma samples is associated with reduced relapse-free survival (A, C) and overall survival (B, D), respectively. (E, F) The presence of ctDNA in plasma samples either prior to primary resection or during surveillance is associated with reduced relapse-free survival and overall survival. Analysis was performed using a log-rank test, and the number of patients at risk at any given time point is indicated.