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. 1985 Jul 1;229(1):265–268. doi: 10.1042/bj2290265

Differential binding of glycine- and taurine-conjugated bile acids to insoluble calcium phosphate.

R Van der Meer, H T De Vries
PMCID: PMC1145176  PMID: 4038261

Abstract

It is demonstrated that bile acids bind to insoluble calcium phosphate at pH values beyond 5.5. Significant binding occurs with glycine-conjugated dihydroxy bile acids. Results indicate that these bile acids are bound in a micellar mode. Taurine conjugation almost completely inhibits the binding of these bile acids to insoluble calcium phosphate. Since glycine-conjugated dihydroxy bile acids are predominant in the rabbit, but not in the rat, our results suggest an explanation for the intriguing species-dependence of casein-induced hypercholesterolaemia, which is high in the rabbit but absent in the rat.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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