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Signal Transduction and Targeted Therapy logoLink to Signal Transduction and Targeted Therapy
. 2024 Oct 4;9:265. doi: 10.1038/s41392-024-01972-4

Correction: CDK4/6 inhibition blocks cancer metastasis through a USP51-ZEB1-dependent deubiquitination mechanism

Zhen Zhang 1, Jianjun Li 1, Yang Ou 1, Guang Yang 2, Kaiyuan Deng 1, Qiong Wang 1, Zhaoyang Wang 1, Wenhao Wang 1, Quansheng Zhang 3, Hang Wang 1, Wei Sun 1, Peiqing Sun 4, Shuang Yang 1,
PMCID: PMC11452405  PMID: 39366949

Correction to: Signal Transduction and Targeted Therapy (2020) 5:25; 10.1038/s41392-020-0118-x, published online 11 March 2020

The authors noticed one inadvertent mistake in Supplementary Figure S5d that needs to be corrected. The image of shCDK6-1 (20h) in the ZEB1/231 group was repeatedly inserted as the image of shCDK4-2 (20h) by mistake during the preparation of the figures. The correct image of shCDK4-2 (20h) in the ZEB1/231 group is provided as follows. The accompanying quantification of Supplementary Figure S5d was not affected by this mistake, since the authors previously used the correct raw images to perform statistical analysis. The key findings of the article are not affected by these corrections.graphic file with name 41392_2024_1972_Figa_HTML.jpg

Supplementary Figure. S5d. Wound healing analysis in CDK4/6-interfered MDA-MB-231 cells in the presence or absence of rescued ZEB1 expression. *P < 0.05, **P < 0.01, ***P < 0.001 vs. respective control by unpaired Student’s t-test.

The authors noticed one inadvertent mistake that occurred during the preparation of Figure 1d (left panel) that needs to be corrected. The band of ZEB1 in the IP:ZEB1 group (left panel of Supplementary Figure S1g) was repeatedly inserted as the band of ZEB1 in the Input group (left panel of Figure 1d) by mistake during the preparation of the figures. The correct band of ZEB1 in the Input group (left panel of Figure 1d) is provided as follows. The key findings of the article are not affected by these corrections. The original article has been corrected.graphic file with name 41392_2024_1972_Figb_HTML.jpg

Figure. 1d (left panel). Coimmunoprecipitation analysis of ZEB1 protein ubiquitination in MDA-MB-231 cells after treatment with palbociclib for 48 h. The cells were treated with MG132 for 12 h prior to harvest.

The authors noticed some inaccurate information in the “Tissue microarray and immunohistochemistry (IHC) scoring” section of the materials & methods that needs to be corrected. The sentence of “Twenty fresh breast invasive ductal carcinoma tissues were obtained from the First Affiliated Hospital of Chongqing Medical University (Chongqing, China), 100 breast invasive ductal carcinoma tissues were obtained from Alenabio Biotechnology Ltd., Xi’an, China (catalog number: BC081120c), and 145 breast invasive ductal carcinoma tissues with overall survival rate were obtained from Shanghai Outdo Biotech Co., Ltd., China. All of the patients had histologically confirmed invasive ductal carcinoma breast cancer (Tables S4–S7).” is changed to “Twenty fresh breast carcinoma tissues were obtained from the First Affiliated Hospital of Chongqing Medical University (Chongqing, China) and the study was approved by the Ethics Committee of the First Affiliated Hospital of Chongqing Medical University, tissue microarrays containing 100 breast carcinoma tissues were obtained from Alenabio Biotechnology Co., Ltd., Xi’an, China (catalog number: BC081120c), and tissue microarrays containing 145 breast carcinoma tissues with overall survival rate were obtained from Shanghai Outdo Biotech Co., Ltd., China. Written informed consent for using clinical information and tissue samples was obtained from all patients. All of the patients had histologically confirmed breast carcinoma (Tables S4–S7)”. The key findings of the article are not affected by these corrections.

The original article has been corrected.

Supplementary information

Fig S5d (114.2KB, jpg)

Supplementary information

The online version contains supplementary material available at 10.1038/s41392-024-01972-4.

Associated Data

This section collects any data citations, data availability statements, or supplementary materials included in this article.

Supplementary Materials

Fig S5d (114.2KB, jpg)

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