Abstract
The use of polyvinylpyrrolidone, an inert polymer resembling plasma proteins in its colligative effects, in the testing of micrococcaceae for sensitivity to methicillin and cephradine is described. Generally results are quite comparable with those of conventional methods. The absence of any inhibitory effect of the polymer compared to sodium chloride, and its physiological inertia compared to sucrose, along with its suitability for sterilisation by autoclaving are seen as advantages. It is suggested that the use of this substance may give results which are more applicable to the in vivo situation. This may apply particularly in the case of cephradine.
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Selected References
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- Annear D. I. The effect of temperature on resistance of Staphylococcus aureus to methicillin and some other antibioics. Med J Aust. 1968 Mar 16;1(11):444–446. [PubMed] [Google Scholar]
- Churcher G. M. A screening test for the detection of methicillin-resistant staphylococci. J Clin Pathol. 1968 Mar;21(2):213–217. doi: 10.1136/jcp.21.2.213. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Greenwood D., O'Grady F. Comparison of the responses of Escherichia coli and proteus mirabilis to seven beta-lactam antibodies. J Infect Dis. 1973 Aug;128(2):211–222. doi: 10.1093/infdis/128.2.211. [DOI] [PubMed] [Google Scholar]
- Greenwood D., O'Grady F. The comparative performance of beta-lactam antibiotics against ampicillin sensitive Escherichia coli in conditions simulating those of the infected urinary bladder. Br J Exp Pathol. 1974 Jun;55(3):245–250. [PMC free article] [PubMed] [Google Scholar]
- Greenwood D., O'Grady F. The effect of osmolality on the response of Escherichia coli and Proteus mirabilis to penicillins. Br J Exp Pathol. 1972 Oct;53(5):457–464. [PMC free article] [PubMed] [Google Scholar]
- KUTOR J. Koraszülöttek magicterusának megelozése peristonnal. Gyermekgyogyaszat. 1958 Jan-Mar;9(1-3):41–46. [PubMed] [Google Scholar]
- Lawson J. W., Douglas J. T. Induction and reversion of the L-form of Neisseria gonorrhoeae. Can J Microbiol. 1973 Sep;19(9):1145–1151. doi: 10.1139/m73-182. [DOI] [PubMed] [Google Scholar]
- Pratt B. C. Cell-wall deficiencies in L-forms of Staphylococcus aureus. J Gen Microbiol. 1966 Jan;42(1):115–122. doi: 10.1099/00221287-42-1-115. [DOI] [PubMed] [Google Scholar]
- WILLIAMS R. E. L FORMS OF STAPHYLOCOCCUS AUREUS. J Gen Microbiol. 1963 Nov;33:325–334. doi: 10.1099/00221287-33-2-325. [DOI] [PubMed] [Google Scholar]