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Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1978 Jul;31(7):648–653. doi: 10.1136/jcp.31.7.648

Lysosomal enzyme cytochemistry of blood neutrophils.

J T Wozniak, T L Orchard, P H Mackie, D K Mistry, J Stuart
PMCID: PMC1145368  PMID: 353080

Abstract

Patients with bacterial infection may show altered membrane permeability of the primary azurophilic lysosomes of blood neutrophils. A new enzyme cytochemical technique, sensitive to increased membrane permeability caused by contact of neutrophils with acetone, saponin, low pH, Streptolysin O, bacteria, and nylon wool, has been developed. The method is of potential value as a screening test for bacterial infection and for detecting neutrophil damage during filtration leucopheresis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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