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. 1978 Aug;31(8):757–760. doi: 10.1136/jcp.31.8.757

Giant lymph node hyperplasia of the mediastinum and refractory anaemia.

C G Geary, H Fox
PMCID: PMC1145402  PMID: 690239

Abstract

An example is described of the syndrome of refractory anaemia in association with the plasma cell variant of giant lymph node hyperplasia of the mediastinum; the anaemia responded to removal of the lymphoid mass. The entity of giant lymph node hyperplasia is discussed and its relationship to the haematological syndrome is considered.

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Selected References

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  1. ABELL M. R. Lymphnodal hamartoma versus thymic choristoma of pulmonary hilum. AMA Arch Pathol. 1957 Nov;64(5):584–588. [PubMed] [Google Scholar]
  2. Boxer L. A., Boxer G. J., Flair R. C., Engstrom P. F., Brown G. S. Angiomatous lymphoid hamartoma associated with chronic anemia, hypoferremia, and hypergammaglobulinemia. J Pediatr. 1972 Jul;81(1):66–70. doi: 10.1016/s0022-3476(72)80375-5. [DOI] [PubMed] [Google Scholar]
  3. Burgert E. O., Jr, Gilchrist G. S., Fairbanks V. F., Lynn H. B., Dukes P. P., Harrison E. G., Jr Intra-abdominal, angiofollicular lymph node hyperplasia (plasma-cell variant) with an antierythropoietic factor. Mayo Clin Proc. 1975 Sep;50(9):542–546. [PubMed] [Google Scholar]
  4. CASTLEMAN B., IVERSON L., MENENDEZ V. P. Localized mediastinal lymphnode hyperplasia resembling thymoma. Cancer. 1956 Jul-Aug;9(4):822–830. doi: 10.1002/1097-0142(195607/08)9:4<822::aid-cncr2820090430>3.0.co;2-4. [DOI] [PubMed] [Google Scholar]
  5. Cartwright G. E., Lee G. R. The anaemia of chronic disorders. Br J Haematol. 1971 Aug;21(2):147–152. doi: 10.1111/j.1365-2141.1971.tb03424.x. [DOI] [PubMed] [Google Scholar]
  6. Dorfman R. F., Warnke R. Lymphadenopathy simulating the malignant lymphomas. Hum Pathol. 1974 Sep;5(5):519–550. doi: 10.1016/s0046-8177(74)80005-5. [DOI] [PubMed] [Google Scholar]
  7. Fisher E. R., Sieracki J. C., Goldenberg D. M. Identity and nature of isolated lymphoid tumors (so-called nodal hyperplasia, hamartoma, and angiomatous hamartoma) as revealed by histologic, electron microscopic, and heterotransplantation studies. Cancer. 1970 Jun;25(6):1286–1300. doi: 10.1002/1097-0142(197006)25:6<1286::aid-cncr2820250606>3.0.co;2-u. [DOI] [PubMed] [Google Scholar]
  8. Kahn L. B., Ranchod M., Stables D. P., King H., Yudelman I. Giant lymph node hyperplasia with haematological abnormalities. S Afr Med J. 1973 May 19;47(19):811–816. [PubMed] [Google Scholar]
  9. Keller A. R., Hochholzer L., Castleman B. Hyaline-vascular and plasma-cell types of giant lymph node hyperplasia of the mediastinum and other locations. Cancer. 1972 Mar;29(3):670–683. doi: 10.1002/1097-0142(197203)29:3<670::aid-cncr2820290321>3.0.co;2-#. [DOI] [PubMed] [Google Scholar]
  10. LATTES R., PACHTER M. R. Benign lymphoid masses of probable hamartomatous nature. Analysis of 12 cases. Cancer. 1962 Jan-Feb;15:197–214. doi: 10.1002/1097-0142(196201/02)15:1<197::aid-cncr2820150128>3.0.co;2-6. [DOI] [PubMed] [Google Scholar]
  11. LEE S. L., ROSNER F., RIVERO I., FELDMAN F., HURWITZ A. REFRACTORY ANEMIA WITH ABNORMAL IRON METABOLISM: ITS REMISSION AFTER RESECTION OF HYPERPLASTIC MEDIASTINAL LYMPH NODES. N Engl J Med. 1965 Apr 15;272:761–766. doi: 10.1056/NEJM196504152721502. [DOI] [PubMed] [Google Scholar]
  12. Namba M., Ogura T., Hirao F., Yamamura Y. Mediastinal lymph node hyperplasia. A report of two cases, hyaline-vascular type and plasma-cell type. Med J Osaka Univ. 1973 Mar;23(4):239–247. [PubMed] [Google Scholar]
  13. Notomi A., Iwamoto Y., Kikuchi M. Giant lymph node hyperplasia with fever, anemia, hypergammaglobulinemia and jaundice. Nihon Ketsueki Gakkai Zasshi. 1976 Feb;39(1):11–19. [PubMed] [Google Scholar]
  14. Sethi G., Kepes J. J. Intrathoracic angiomatous lymphoid hamartomas. A report of three cases, one of iron refractory anemia and retarded growth. J Thorac Cardiovasc Surg. 1971 Apr;61(4):657–664. [PubMed] [Google Scholar]
  15. Van den Ende J., Kahn L. B., Jacobs P. Letter: Giant lymph node hyperplasia with haematological abnormality. S Afr Med J. 1975 Feb 8;49(6):170–170. [PubMed] [Google Scholar]
  16. ZETTERGREN L. Probably neoplastic proliferation of lymphoid tissue (follicular lympho-reticuloma). Reports of four cases with a survey of literature. Acta Pathol Microbiol Scand. 1961;51:113–126. doi: 10.1111/j.1699-0463.1961.tb00350.x. [DOI] [PubMed] [Google Scholar]

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