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Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1978 Sep;31(9):855–858. doi: 10.1136/jcp.31.9.855

Use of sensitivity discs as primary antibiotic standards in MIC determination.

D J Flowers
PMCID: PMC1145429  PMID: 711916

Abstract

A method for the determination of minimum inhibitory concentration (MICs) is described, in which commercially prepared antibiotic sensitivity testing discs are used as primary antibiotic standards from which the necessary dilutions are prepared in WHO Perspex haemagglutination plates. The materials required are readily available in most laboratories at a cost in time and reagents that compares favourably with most traditional methods of MIC testing. The same techniques may also be used to demonstrate combined antibiotic activity and to differentiate between bacteriostatic and bactericidal activity, with little expenditure of laboratory resources.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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