Abstract
Serum cystyl aminopeptidase (CAS) activity was estimated at 36 weeks' gestation in 209 normotensive pregnancies. The highest activity was found in 31 women who had spontaneous deliveries before 38 weeks' gestation and the lowest in 76 women who were induced after term. The enzyme levels in 117 women who developed hypertension of pregnancy were higher than for normotensives; the highest levels were found in 32 women with pre-eclampsia. A correlation was found between serum CAS activity at 36 weeks' gestation and the birth weight of babies of women who went into spontaneous labour at term (277 to 283 days' gestation).
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Selected References
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- Chapman L., Burrows-Peakin R., Jowett T. P., Rege V. P., Silk E. The normal serum cystine aminopeptidase (CAP) range in pregnancy. Clin Chim Acta. 1973 Aug 17;47(1):89–92. doi: 10.1016/0009-8981(73)90063-6. [DOI] [PubMed] [Google Scholar]
- Chapman L., Silk E., Skupny A., Tooth E. A., Barnes A. Spectrofluorimetric assay of serum cystine aminopeptidase in normal and diabetic pregnancy compared with total oestrogen excretion. J Obstet Gynaecol Br Commonw. 1971 May;78(5):435–443. doi: 10.1111/j.1471-0528.1971.tb00298.x. [DOI] [PubMed] [Google Scholar]
- Durham B. H. Spectrophotometric end-point method for assay of serum cystyl-aminopeptidase in pregnancy. Clin Chem. 1976 Jan;22(1):79–82. [PubMed] [Google Scholar]
- Hurry D. J., Tovey J. E., Robinson D. A., Beynon C. L., Cooper K. Cystine aminopeptidase in normal and complicated pregnancies. J Obstet Gynaecol Br Commonw. 1972 Sep;79(9):788–793. doi: 10.1111/j.1471-0528.1972.tb12921.x. [DOI] [PubMed] [Google Scholar]
- Klimek R. Relative duration of human pregnancy and oxytocin therapy. I. Gynaecologia. 1967;163(1):48–60. doi: 10.1159/000302819. [DOI] [PubMed] [Google Scholar]
- Petrucco O. M., Chellier K., Fishtall A. Diagnosis of intrauterine fetal growth retardation by serial serum oxytocinase, urinary oestrogen and serum heat stable alkaline phosphatase (HSAP) estimations in uncomplicated and hypertensive pregnancies. J Obstet Gynaecol Br Commonw. 1973 Jun;80(6):499–507. doi: 10.1111/j.1471-0528.1973.tb15970.x. [DOI] [PubMed] [Google Scholar]
- Sjöholm I., Yman L. Degradation of oxytocin, lysine-vasopressin, angiotensin II and angiotensin-II-amide by oxytocinase (cystine aminopeptidase). Acta Pharm Suec. 1967 Apr;4(2):65–76. [PubMed] [Google Scholar]
