Skip to main content
Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1979 Apr;32(4):356–360. doi: 10.1136/jcp.32.4.356

Haematological features of angioimmunoblastic lymphadenopathy with dysproteinaemia.

R L Brearley, J Chapman, M H Cullen, M A Horton, A G Stansfeld, A H Waters
PMCID: PMC1145672  PMID: 447869

Abstract

A study of seven patients with AILD has confirmed previously reported cytological and immunological changes in the peripheral blood. In themselves these changes should not be considered as specific. Histological examination of the bone marrow may show more characteristic lesions which involve haemopoietic, lymphoid, and stromal cells. Three patients had bone marrow features similar to myelofibrosis, which are considered to be diagnostic of AILD.

Full text

PDF

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Budman D. R., Steinberg A. D. Hematologic aspects of systemic lupus erythematosus. Current concepts. Ann Intern Med. 1977 Feb;86(2):220–229. doi: 10.7326/0003-4819-86-2-220. [DOI] [PubMed] [Google Scholar]
  2. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 10-1978. N Engl J Med. 1978 Mar 16;298(11):613–620. doi: 10.1056/NEJM197803162981108. [DOI] [PubMed] [Google Scholar]
  3. Flandrin G. Adénopathies angio-immunoblastiques avec anémie auto-immune et hyperimmunoglobulinémie polyclonale. Nouv Presse Med. 1976 Jun 12;5(24):1521–1524. [PubMed] [Google Scholar]
  4. Frizzera G., Moran E. M., Rappaport H. Angio-immunoblastic lymphadenopathy with dysproteinaemia. Lancet. 1974 Jun 1;1(7866):1070–1073. doi: 10.1016/s0140-6736(74)90553-4. [DOI] [PubMed] [Google Scholar]
  5. Frizzera G., Moran E. M., Rappaport H. Angio-immunoblastic lymphadenopathy. Diagnosis and clinical course. Am J Med. 1975 Dec;59(6):803–818. doi: 10.1016/0002-9343(75)90466-0. [DOI] [PubMed] [Google Scholar]
  6. Graham R. C., Jr Letter: Pathogenesis of vascular proliferation in angio-immunoblastic lymphadenopathy with dysproteinaemia. Lancet. 1974 Sep 14;2(7881):666–666. doi: 10.1016/s0140-6736(74)92002-9. [DOI] [PubMed] [Google Scholar]
  7. Hartsock R. J. Postvaccinial lymphadenitis. Hyperplasia of lymphoid tissue that simulates malignant lymphomas. Cancer. 1968 Apr;21(4):632–649. doi: 10.1002/1097-0142(196804)21:4<632::aid-cncr2820210415>3.0.co;2-o. [DOI] [PubMed] [Google Scholar]
  8. Lennert K., Stein H., Kaiserling E. Cytological and functional criteria for the classification of malignant lymphomata. Br J Cancer Suppl. 1975 Mar;2:29–43. [PMC free article] [PubMed] [Google Scholar]
  9. Lukes R. J., Tindle B. H. Immunoblastic lymphadenopathy. A hyperimmune entity resembling Hodgkin's disease. N Engl J Med. 1975 Jan 2;292(1):1–8. doi: 10.1056/NEJM197501022920101. [DOI] [PubMed] [Google Scholar]
  10. McMillan R., Longmire R. L., Yelenosky R., Lang J. E., Heath V., Craddock C. G. Immunoglobulin synthesis by human lymphoid tissues: normal bone marrow as a major site of IgG production. J Immunol. 1972 Dec;109(6):1386–1394. [PubMed] [Google Scholar]
  11. Nathwani B. N., Rappaport H., Moran E. M., Pangalis G. A., Kim H. Malignant lymphoma arising in angioimmunoblastic lymphadenopathy. Cancer. 1978 Feb;41(2):578–606. doi: 10.1002/1097-0142(197802)41:2<578::aid-cncr2820410226>3.0.co;2-8. [DOI] [PubMed] [Google Scholar]
  12. Neiman R. S., Dervan P., Haudenschild C., Jaffe R. Angioimmunoblastic lymphadenopathy: an ultrastructural and immunologic study with review of the literature. Cancer. 1978 Feb;41(2):507–518. doi: 10.1002/1097-0142(197802)41:2<507::aid-cncr2820410218>3.0.co;2-d. [DOI] [PubMed] [Google Scholar]
  13. Pangalis G. A., Moran E. M., Rappaport H. Blood and bone marrow findings in angioimmunoblastic lymphadenopathy. Blood. 1978 Jan;51(1):71–83. [PubMed] [Google Scholar]
  14. RUBIN H. Antibody elution from red blood cells. J Clin Pathol. 1963 Jan;16:70–73. doi: 10.1136/jcp.16.1.70. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Rosas-Uribe A., Variakojis D., Rappaport H. Proteinaceous precipitate in nodular (follicular) lymphomas. Cancer. 1973 Mar;31(3):532–542. doi: 10.1002/1097-0142(197303)31:3<534::aid-cncr2820310307>3.0.co;2-n. [DOI] [PubMed] [Google Scholar]
  16. SALTZSTEIN S. L., ACKERMAN L. V. Lymphadenopathy induced by anticonvulsant drugs and mimicking clinically pathologically malignant lymphomas. Cancer. 1959 Jan-Feb;12(1):164–182. doi: 10.1002/1097-0142(195901/02)12:1<164::aid-cncr2820120122>3.0.co;2-y. [DOI] [PubMed] [Google Scholar]
  17. Turesson I. Distribution of immunoglobulin-containing cells in human bone marrow and lymphoid tissues. Acta Med Scand. 1976;199(4):293–304. doi: 10.1111/j.0954-6820.1976.tb06735.x. [DOI] [PubMed] [Google Scholar]
  18. WILLOUGHBY D. A., SPECTOR W. G. THE PRODUCTION OF EOSINOPHILIC DEPOSITS RESEMBLING FIBRINOID BY INJECTIONS OF LYMPH-NODE EXTRACTS. J Pathol Bacteriol. 1964 Oct;88:557–562. doi: 10.1002/path.1700880220. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Publishing Group

RESOURCES