Abstract
A strain of Streptococcus pneumoniae requiring 0.25 mg/1 penicillin to inhibit its growth was isolated from the antrum of a child who had no history of either foreign contacts or previous treatment with penicillin. The penicillin resistance was recognised by chance because the disc used contained substantially less than its stated content of 1.5 unit. When discs containing 2 units were used there was little reduction in size of the zone of inhibition.
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- Howes V. J., Mitchell R. G. Meningitis due to relatively penicillin-resistant pneumococcus. Br Med J. 1976 Apr 24;1(6016):996–996. doi: 10.1136/bmj.1.6016.996. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Jacobs M. R., Gaspar M. N., Robins-Browne R. M., Koornhof H. J. Antimicrobial susceptibility testing of pneumococci. 2. Determination of optimal disc diffusion test for detection of penicillin G resistance. J Antimicrob Chemother. 1980 Jan;6(1):53–64. doi: 10.1093/jac/6.1.53. [DOI] [PubMed] [Google Scholar]
- Meers P. D., Matthews R. B. Multiply resistant pneumococcus. Lancet. 1978 Jul 22;2(8082):219–219. doi: 10.1016/s0140-6736(78)91966-9. [DOI] [PubMed] [Google Scholar]
- Shanson D. C., Rees T., Sinclair L. Ear infection due to penicillin-resistant pneumococcus in immunodeficient child. Lancet. 1979 Nov 3;2(8149):956–956. doi: 10.1016/s0140-6736(79)92648-5. [DOI] [PubMed] [Google Scholar]