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. 1986 Dec 15;240(3):897–903. doi: 10.1042/bj2400897

Thiyl and phenoxyl free radicals and NADH. Direct observation of one-electron oxidation.

L G Forni, R L Willson
PMCID: PMC1147504  PMID: 3827879

Abstract

Absolute rate constants for the reaction of NADH with thiyl free radicals derived from various sulphur-containing compounds of biological significance were measured by using the technique of pulse radiolysis. These and related reactions with phenoxyl free radicals are believed to occur through one-electron-transfer processes. Further evidence comes from studies with deuterated NADH. The results support the possibility that, in biochemical systems, thiols may act as catalysts linking hydrogen-atom and electron-transfer reactions.

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Selected References

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