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. 1986 Dec 15;240(3):925–927. doi: 10.1042/bj2400925

Accumulation of globotriaosylceramide in a case of leiomyosarcoma.

S C Li, S K Kundu, R Degasperi, Y T Li
PMCID: PMC1147510  PMID: 3827883

Abstract

Analysis of the glycosphingolipid composition in one case of uterine leiomyosarcoma metastasized to the liver showed an accumulation of globotriaosylceramide as compared with normal liver and uterus from which the tumour originated. The structure and the amount of glycosphingolipids were established by using specific glycosidases, permethylation analysis and h.p.l.c. The reason for the accumulation of globotriaosylceramide in leiomyosarcoma remains to be answered.

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Selected References

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