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. 1987 Mar 1;242(2):465–469. doi: 10.1042/bj2420465

Properties of the canalicular bile acid transport system in rat liver.

P J Meier, A S Meier-Abt, J L Boyer
PMCID: PMC1147728  PMID: 3593261

Abstract

4,4-Di-isothiocyanostilbene-2,2'-disulphonic acid inhibition of taurocholate efflux from canalicular vesicles was used to demonstrate that potential driven and 'carrier'-mediated canalicular excretion of taurocholate occur via a common, rather than two separate, pathways. This electrogenic canalicular bile acid 'carrier' preferentially transports trihydroxylated and conjugated dihydroxylated bile acids, but not the unphysiological oxo bile acids, and possibly extends its substrate specificity to other amphipathic molecules such as sulphobromophthalein.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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