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. 2024 Oct 2;16(19):3359. doi: 10.3390/nu16193359

Table 6.

Coefficients of multiple linear regression showing the correlations between circulating markers of redox balance (dependent variables) and inflammation/immune response markers (independent variables).

Unstandardized Coefficients Standardized Coefficients t-Value p-Value
B Std. Error Beta
Dependent: GSSG/GSH
Constant 5.020 6.923 0.725 0.469
ESR 0.075 0.055 0.119 1.373 0.171
Fibrinogen −0.008 0.008 −0.063 0.910 0.364
Ferritin 0.007 0.003 0.176 2.438 0.051
α2-glob 0.478 0.375 0.095 1.274 0.204
Neutro −0.001 0.001 −0.193 −1.724 0.086
Lympho 0.001 0.002 0.041 0.551 0.582
NLR 0.496 0.369 0.164 1.344 0.180
IL-6 0.311 0.187 0.129 1.660 0.098
TNF 0.198 0.298 0.048 0.667 0.506
Model verification: ANOVA, F = 3.503; p < 0.001
Dependent: HNE
Constant 44.563 7.781 5.527 <0.001
ESR 0.095 0.061 0.130 1.553 0.122
Fibrinogen −0.020 0.009 −0.143 −2.134 0.034
Ferritin 0.005 0.003 0.106 1.511 0.132
α2-glob −0.206 0.421 −0.035 −0.490 0.625
Neutro 0.001 0.001 0.173 1.600 0.111
Lympho −0.005 0.002 −0.201 −2.793 0.006
NLR −0.662 0.415 −0.189 −1.595 0.112
IL-6 0.461 0.211 0.164 2.188 0.030
TNF −0.374 0.334 −0.078 −1.117 0.265
Model verification: ANOVA, F = 5.711; p < 0.001
Dependent: MDA
Constant 49.287 16.046 3.053 0.003
ESR 0.118 0.128 0.082 0.925 0.356
Fibrinogen −0.003 0.019 −0.009 −0.130 0.896
Ferritin −0.004 0.007 −0.041 −0.577 0.578
α2-glob 0.441 0.875 0.038 0.504 0.615
Neutro 0.000 0.001 −0.009 −0.077 0.939
Lympho −0.002 0.004 −0.049 −0.647 0.519
NLR −0.114 0.861 −0.016 −0.132 0.895
IL-6 1.281 0.437 0.232 2.931 0.004
TNF 0.808 0.694 0.086 1.165 0.295
Model verification: ANOVA, F = 2.165; p = 0.025

Significant predictive power is formatted in bold. ESR, erythrocyte sedimentation rate; α2-glob, α2-globulins; Neutro, neutrophils; Lympho, lymphocytes; NLR, neutrophil-to-lymphocyte ratio; IL-6, interleukin-6; TNF, tumor necrosis factor; GSSG/GSH, oxidized/reduced glutathione; HNE, hydroxynonenal–protein adducts; MDA, malondialdehyde–protein adducts.