Skip to main content
NCBI home page
Biochemical Journal logoLink to Biochemical Journal
. 1987 Jun 1;244(2):249–261. doi: 10.1042/bj2440249

Biochemistry of bile secretion.

R Coleman 1
PMCID: PMC1147985  PMID: 3311027

Full text

PDF
249

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Accatino L., Simon F. R. Identification and characterization of a bile acid receptor in isolated liver surface membranes. J Clin Invest. 1976 Feb;57(2):496–508. doi: 10.1172/JCI108302. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Ahnen D. J., Brown W. R., Kloppel T. M. Secretory component: the polymeric immunoglobulin receptor. What's in it for the gastroenterologist and hepatologist? Gastroenterology. 1985 Sep;89(3):667–682. doi: 10.1016/0016-5085(85)90467-6. [DOI] [PubMed] [Google Scholar]
  3. Anwer M. S., Kroker R., Hegner D., Petter A. Cholic acid binding to isolated rat liver plasma membranes. Hoppe Seylers Z Physiol Chem. 1977 May;358(5):543–553. doi: 10.1515/bchm2.1977.358.1.543. [DOI] [PubMed] [Google Scholar]
  4. Apstein M. D., Robins S. J. Effect of organic anions on biliary lipids in the rat. Gastroenterology. 1982 Nov;83(5):1120–1126. [PubMed] [Google Scholar]
  5. Apstein M. D., Russo A. R. Ampicillin inhibits biliary cholesterol secretion. Dig Dis Sci. 1985 Mar;30(3):253–256. doi: 10.1007/BF01347893. [DOI] [PubMed] [Google Scholar]
  6. Arias I. M. Mechanisms and consequences of ion transport in the liver. Prog Liver Dis. 1986;8:145–159. [PubMed] [Google Scholar]
  7. BALINT J. A., KYRIAKIDES E. C., SPITZER H. L., MORRISON E. S. LECITHIN FATTY ACID COMPOSITION IN BILE AND PLASMA OF MAN, DOGS, RATS, AND OXEN. J Lipid Res. 1965 Jan;6:96–99. [PubMed] [Google Scholar]
  8. Barnwell S. G., Coleman R. Abnormal secretion of proteins into bile from colchicine-treated isolated perfused rat livers. Biochem J. 1983 Nov 15;216(2):409–414. doi: 10.1042/bj2160409. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Barnwell S. G., Godfrey P. P., Lowe P. J., Coleman R. Biliary protein output by isolated perfused rat livers. Effects of bile salts. Biochem J. 1983 Feb 15;210(2):549–557. doi: 10.1042/bj2100549. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Barnwell S. G., Lowe P. J., Coleman R. Effect of taurochenodeoxycholate or tauroursodeoxycholate upon biliary output of phospholipids and plasma-membrane enzymes, and the extent of cell damage, in isolated perfused rat livers. Biochem J. 1983 Oct 15;216(1):107–111. doi: 10.1042/bj2160107. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Barnwell S. G., Lowe P. J., Coleman R. The effects of colchicine on secretion into bile of bile salts, phospholipids, cholesterol and plasma membrane enzymes: bile salts are secreted unaccompanied by phospholipids and cholesterol. Biochem J. 1984 Jun 15;220(3):723–731. doi: 10.1042/bj2200723. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Berk P. D., Stremmel W. Hepatocellular uptake of organic anions. Prog Liver Dis. 1986;8:125–144. [PubMed] [Google Scholar]
  13. Billington D., Coleman R. Effects of bile salts of human erythrocytes. Plasma membrane vesiculation, phospholipid solubilization and their possible relationships to bile secretion. Biochim Biophys Acta. 1978 May 4;509(1):33–47. doi: 10.1016/0005-2736(78)90005-6. [DOI] [PubMed] [Google Scholar]
  14. Billington D., Evans C. E., Godfrey P. P., Coleman R. Effects of bile salts on the plasma membranes of isolated rat hepatocytes. Biochem J. 1980 May 15;188(2):321–327. doi: 10.1042/bj1880321. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Billington D., Rahman K., Jones T. W., Coleman R., Sykes I. R., Aulak K. S. Phospholipid degradation in, and protein content of, rat fistula bile. Contamination of bile with pancreatic juice. J Hepatol. 1986;3(2):233–240. doi: 10.1016/s0168-8278(86)80032-0. [DOI] [PubMed] [Google Scholar]
  16. Blitzer B. L., Boyer J. L. Cellular mechanisms of bile formation. Gastroenterology. 1982 Feb;82(2):346–357. [PubMed] [Google Scholar]
  17. Bouchier I. A. Biochemistry of gallstone formation. Clin Gastroenterol. 1983 Jan;12(1):25–48. [PubMed] [Google Scholar]
  18. Bouchier I. A. Debits and credits: a current account of cholesterol gall stone disease. Gut. 1984 Oct;25(10):1021–1028. doi: 10.1136/gut.25.10.1021. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Boyer J. L. New concepts of mechanisms of hepatocyte bile formation. Physiol Rev. 1980 Apr;60(2):303–326. doi: 10.1152/physrev.1980.60.2.303. [DOI] [PubMed] [Google Scholar]
  20. Boyer J. L. Tight junctions in normal and cholestatic liver: does the paracellular pathway have functional significance? Hepatology. 1983 Jul-Aug;3(4):614–617. doi: 10.1002/hep.1840030423. [DOI] [PubMed] [Google Scholar]
  21. Chen E. H., Gumucio J. J., Ho N. H., Gumucio D. L. Hepatocytes of Zones 1 and 3 conjugate sulfobromophthalein with glutathione. Hepatology. 1984 May-Jun;4(3):467–476. doi: 10.1002/hep.1840040320. [DOI] [PubMed] [Google Scholar]
  22. Chipman J. K. Bile as a source of potential reactive metabolites. Toxicology. 1982;25(2-3):99–111. doi: 10.1016/0300-483x(82)90022-1. [DOI] [PubMed] [Google Scholar]
  23. Coleman R., Lowe P. J., Billington D. Membrane lipid composition and susceptibility to bile salt damage. Biochim Biophys Acta. 1980 Jun 20;599(1):294–300. doi: 10.1016/0005-2736(80)90075-9. [DOI] [PubMed] [Google Scholar]
  24. De Silva N. S., Siu C. H. Vesicle-mediated transfer of phospholipids to plasma membrane during cell aggregation of Dictyostelium discoideum. J Biol Chem. 1981 Jun 10;256(11):5845–5850. [PubMed] [Google Scholar]
  25. DeGrella R. F., Simoni R. D. Intracellular transport of cholesterol to the plasma membrane. J Biol Chem. 1982 Dec 10;257(23):14256–14262. [PubMed] [Google Scholar]
  26. Delacroix D. L., Furtado-Barreira G., de Hemptinne B., Goudswaard J., Dive C., Vaerman J. P. The liver in the IgA secretory immune system. Dogs, but not rats and rabbits, are suitable models for human studies. Hepatology. 1983 Nov-Dec;3(6):980–988. doi: 10.1002/hep.1840030616. [DOI] [PubMed] [Google Scholar]
  27. Dive C., Heremans J. F. Nature and origin of the proteins of bile. I. A comparative analysis of serum and bile proteins in man. Eur J Clin Invest. 1974 Aug;4(4):235–239. doi: 10.1111/j.1365-2362.1974.tb00398.x. [DOI] [PubMed] [Google Scholar]
  28. Dive C., Nadalini R. A., Vaerman J. P., Heremans J. F. Origin and nature of the proteins of bile. II. A comparative analysis of serum, hepatic lymph and bile proteins in the dog. Eur J Clin Invest. 1974 Aug;4(4):241–246. doi: 10.1111/j.1365-2362.1974.tb00399.x. [DOI] [PubMed] [Google Scholar]
  29. Duffy M. C., Blitzer B. L., Boyer J. L. Direct determination of the driving forces for taurocholate uptake into rat liver plasma membrane vesicles. J Clin Invest. 1983 Oct;72(4):1470–1481. doi: 10.1172/JCI111103. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. Elias E., Iqbal S., Knutton S., Hickey A., Coleman R. Increased tight junction permeability: a possible mechanism of oestrogen cholestasis. Eur J Clin Invest. 1983 Oct;13(5):383–390. doi: 10.1111/j.1365-2362.1983.tb00118.x. [DOI] [PubMed] [Google Scholar]
  31. Erlinger S. Hepatocyte bile secretion: current views and controversies. Hepatology. 1981 Jul-Aug;1(4):352–359. doi: 10.1002/hep.1840010413. [DOI] [PubMed] [Google Scholar]
  32. Evans W. H. A biochemical dissection of the functional polarity of the plasma membrane of the hepatocyte. Biochim Biophys Acta. 1980 May 27;604(1):27–64. doi: 10.1016/0005-2736(80)90584-2. [DOI] [PubMed] [Google Scholar]
  33. Evans W. H., Flint N. Subfractionation of hepatic endosomes in Nycodenz gradients and by free-flow electrophoresis. Separation of ligand-transporting and receptor-enriched membranes. Biochem J. 1985 Nov 15;232(1):25–32. doi: 10.1042/bj2320025. [DOI] [PMC free article] [PubMed] [Google Scholar]
  34. Evans W. H., Hardison W. G. Phospholipid, cholesterol, polypeptide and glycoprotein composition of hepatic endosome subfractions. Biochem J. 1985 Nov 15;232(1):33–36. doi: 10.1042/bj2320033. [DOI] [PMC free article] [PubMed] [Google Scholar]
  35. Evans W. H., Kremmmer T., Culvenor J. G. Role of membranes in bile formation. Comparison of the composition of bile and a liver bile-canalicular plasma-membrane subfraction. Biochem J. 1976 Mar 15;154(3):589–595. doi: 10.1042/bj1540589. [DOI] [PMC free article] [PubMed] [Google Scholar]
  36. Forker E. L. Mechanisms of hepatic bile formation. Annu Rev Physiol. 1977;39:323–347. doi: 10.1146/annurev.ph.39.030177.001543. [DOI] [PubMed] [Google Scholar]
  37. Forte T. M. Primary hepatocytes in monolayer culture: a model for studies on lipoprotein metabolism. Annu Rev Physiol. 1984;46:403–415. doi: 10.1146/annurev.ph.46.030184.002155. [DOI] [PubMed] [Google Scholar]
  38. Fry J. R. Preparation of mammalian hepatocytes. Methods Enzymol. 1981;77:130–137. doi: 10.1016/s0076-6879(81)77017-4. [DOI] [PubMed] [Google Scholar]
  39. Gebhardt R., Jung W. Biliary secretion of sodium fluorescein in primary monolayer cultures of adult rat hepatocytes and its stimulation by nicotinamide. J Cell Sci. 1982 Aug;56:233–244. doi: 10.1242/jcs.56.1.233. [DOI] [PubMed] [Google Scholar]
  40. Gebhardt R., Jung W., Robenek H. Primary cultures of rat hepatocytes as a model system of canalicular development, biliary secretion, and intrahepatic cholestasis. I. Distribution of filipin-cholesterol complexes during de novo formation of bile canaliculi. Eur J Cell Biol. 1982 Nov;29(1):68–76. [PubMed] [Google Scholar]
  41. Godfrey P. P., Warner M. J., Coleman R. Enzymes and proteins in bile. Variations in output in rat cannula bile during and after depletion of the bile-salt pool. Biochem J. 1981 Apr 15;196(1):11–16. doi: 10.1042/bj1960011. [DOI] [PMC free article] [PubMed] [Google Scholar]
  42. Goldman I. S., Jones A. L., Hradek G. T., Huling S. Hepatocyte handling of immunoglobulin A in the rat: the role of microtubules. Gastroenterology. 1983 Jul;85(1):130–140. [PubMed] [Google Scholar]
  43. Goldsmith M. A., Huling S., Jones A. L. Hepatic handling of bile salts and protein in the rat during intrahepatic cholestasis. Gastroenterology. 1983 May;84(5 Pt 1):978–986. [PubMed] [Google Scholar]
  44. Graf J., Gautam A., Boyer J. L. Isolated rat hepatocyte couplets: a primary secretory unit for electrophysiologic studies of bile secretory function. Proc Natl Acad Sci U S A. 1984 Oct;81(20):6516–6520. doi: 10.1073/pnas.81.20.6516. [DOI] [PMC free article] [PubMed] [Google Scholar]
  45. Graf J., Petersen O. H. Cell membrane potential and resistance in liver. J Physiol. 1978 Nov;284:105–126. doi: 10.1113/jphysiol.1978.sp012530. [DOI] [PMC free article] [PubMed] [Google Scholar]
  46. Gumucio J. J., Balabaud C., Miller D. L., DeMason L. J., Appelman H. D., Stoecker T. J., Franzblau D. R. Bile secretion and liver cell heterogeneity in the rat. J Lab Clin Med. 1978 Feb;91(2):350–362. [PubMed] [Google Scholar]
  47. Gumucio J. J., Miller D. L. Functional implications of liver cell heterogeneity. Gastroenterology. 1981 Feb;80(2):393–403. [PubMed] [Google Scholar]
  48. Hardison W. G., Apter J. T. Micellar theory of biliary cholesterol excretion. Am J Physiol. 1972 Jan;222(1):61–67. doi: 10.1152/ajplegacy.1972.222.1.61. [DOI] [PubMed] [Google Scholar]
  49. Hardison W. G., Hatoff D. E., Miyai K., Weiner R. G. Nature of bile acid maximum secretory rate in the rat. Am J Physiol. 1981 Oct;241(4):G337–G343. doi: 10.1152/ajpgi.1981.241.4.G337. [DOI] [PubMed] [Google Scholar]
  50. Harmatz P. R., Kleinman R. E., Bunnell B. W., Bloch K. J., Walker W. A. Hepatobiliary clearance of IgA immune complexes formed in the circulation. Hepatology. 1982 May-Jun;2(3):328–333. doi: 10.1002/hep.1840020307. [DOI] [PubMed] [Google Scholar]
  51. Hatoff D. E., Hardison W. G. Bile acid-dependent secretion of alkaline phosphatase in rat bile. Hepatology. 1982 Jul-Aug;2(4):433–439. doi: 10.1002/hep.1840020407. [DOI] [PubMed] [Google Scholar]
  52. Henderson C. J., Percy-Robb I. W., Hayes J. D. Purification of bile acid-binding proteins from rat hepatic cytosol. Use of a photoaffinity label to detect novel Y' binders. Biochim Biophys Acta. 1986 Feb 12;875(2):270–285. doi: 10.1016/0005-2760(86)90177-3. [DOI] [PubMed] [Google Scholar]
  53. Hoffman N. E., Donald D. E., Hosmann A. F. Effect of primary bile acids on bile lipid secretion from perfused dog liver. Am J Physiol. 1975 Sep;229(3):714–720. doi: 10.1152/ajplegacy.1975.229.3.714. [DOI] [PubMed] [Google Scholar]
  54. Hoffman N. E., Iser J. H., Smallwood R. A. Hepatic bile acid transport: effect of conjugation and position of hydroxyl groups. Am J Physiol. 1975 Aug;229(2):298–302. doi: 10.1152/ajplegacy.1975.229.2.298. [DOI] [PubMed] [Google Scholar]
  55. Hofmann A. F., Roda A. Physicochemical properties of bile acids and their relationship to biological properties: an overview of the problem. J Lipid Res. 1984 Dec 15;25(13):1477–1489. [PubMed] [Google Scholar]
  56. Holzbach R. T., Kibe A., Thiel E., Howell J. H., Marsh M., Hermann R. E. Biliary proteins. Unique inhibitors of cholesterol crystal nucleation in human gallbladder bile. J Clin Invest. 1984 Jan;73(1):35–45. doi: 10.1172/JCI111204. [DOI] [PMC free article] [PubMed] [Google Scholar]
  57. Häussinger D. Hepatocyte heterogeneity in glutamine and ammonia metabolism and the role of an intercellular glutamine cycle during ureogenesis in perfused rat liver. Eur J Biochem. 1983 Jun 15;133(2):269–275. doi: 10.1111/j.1432-1033.1983.tb07458.x. [DOI] [PubMed] [Google Scholar]
  58. Iga T., Klaassen C. D. Hepatic extraction of bile acids in rats. Biochem Pharmacol. 1982 Jan 15;31(2):205–209. [PubMed] [Google Scholar]
  59. Inoue M., Kinne R., Tran T., Arias I. M. Taurocholate transport by rat liver canalicular membrane vesicles. Evidence for the presence of an Na+-independent transport system. J Clin Invest. 1984 Mar;73(3):659–663. doi: 10.1172/JCI111257. [DOI] [PMC free article] [PubMed] [Google Scholar]
  60. Inoue M., Kinne R., Tran T., Arias I. M. Taurocholate transport by rat liver sinusoidal membrane vesicles: evidence of sodium cotransport. Hepatology. 1982 Sep-Oct;2(5):572–579. doi: 10.1002/hep.1840020510. [DOI] [PubMed] [Google Scholar]
  61. Inoue M., Kinne R., Tran T., Biempica L., Arias I. M. Rat liver canalicular membrane vesicles. Isolation and topological characterization. J Biol Chem. 1983 Apr 25;258(8):5183–5188. [PubMed] [Google Scholar]
  62. Jaeschke H., Krell H., Pfaff E. No increase of biliary permeability in ethinylestradiol-treated rats. Gastroenterology. 1983 Oct;85(4):808–814. [PubMed] [Google Scholar]
  63. Javitt N. B. Hepatic bile formation (first of two parts). N Engl J Med. 1976 Dec 23;295(26):1464–1469. doi: 10.1056/NEJM197612232952606. [DOI] [PubMed] [Google Scholar]
  64. Jones A. L., Hradek G. T., Renston R. H., Wong K. Y., Karlaganis G., Paumgartner G. Autoradiographic evidence for hepatic lobular concentration gradient of bile acid derivative. Am J Physiol. 1980 Mar;238(3):G233–G237. doi: 10.1152/ajpgi.1980.238.3.G233. [DOI] [PubMed] [Google Scholar]
  65. Jones A. L., Renston R. H., Burwen S. J. Uptake and intracellular disposition of plasma-derived proteins and apoproteins by hepatocytes. Prog Liver Dis. 1982;7:51–69. [PubMed] [Google Scholar]
  66. Jones A. L., Schmucker D. L., Mooney J. S., Ockner R. K., Adler R. D. Alterations in hepatic pericanalicular cytoplasm during enhanced bile secretory activity. Lab Invest. 1979 Apr;40(4):512–517. [PubMed] [Google Scholar]
  67. Jones A. L., Schmucker D. L., Renston R. H., Murakami T. The architecture of bile secretion. A morphological perspective of physiology. Dig Dis Sci. 1980 Aug;25(8):609–629. doi: 10.1007/BF01318875. [DOI] [PubMed] [Google Scholar]
  68. Jungermann K., Katz N. Functional hepatocellular heterogeneity. Hepatology. 1982 May-Jun;2(3):385–395. doi: 10.1002/hep.1840020316. [DOI] [PubMed] [Google Scholar]
  69. Kan K. S., Coleman R. 1-Naphthylisothiocyanate-induced permeability of hepatic tight junctions to proteins. Biochem J. 1986 Sep 1;238(2):323–328. doi: 10.1042/bj2380323. [DOI] [PMC free article] [PubMed] [Google Scholar]
  70. Kibe A., Dudley M. A., Halpern Z., Lynn M. P., Breuer A. C., Holzbach R. T. Factors affecting cholesterol monohydrate crystal nucleation time in model systems of supersaturated bile. J Lipid Res. 1985 Sep;26(9):1102–1111. [PubMed] [Google Scholar]
  71. Klaassen C. D., Watkins J. B., 3rd Mechanisms of bile formation, hepatic uptake, and biliary excretion. Pharmacol Rev. 1984 Mar;36(1):1–67. [PubMed] [Google Scholar]
  72. Kleinman R. E., Harmatz P. R., Walker W. A. The liver: an integral part of the enteric mucosal immune system. Hepatology. 1982 May-Jun;2(3):379–384. doi: 10.1002/hep.1840020315. [DOI] [PubMed] [Google Scholar]
  73. Kloppel T. M., Brown W. R., Reichen J. Mechanisms of secretion of proteins into bile: studies in the perfused rat liver. Hepatology. 1986 Jul-Aug;6(4):587–594. doi: 10.1002/hep.1840060407. [DOI] [PubMed] [Google Scholar]
  74. Kramer W., Bickel U., Buscher H. P., Gerok W., Kurz G. Bile-salt-binding polypeptides in plasma membranes of hepatocytes revealed by photoaffinity labelling. Eur J Biochem. 1982 Dec;129(1):13–24. doi: 10.1111/j.1432-1033.1982.tb07015.x. [DOI] [PubMed] [Google Scholar]
  75. Krell H., Höke H., Pfaff E. Development of intrahepatic cholestasis by alpha-naphthylisothiocyanate in rats. Gastroenterology. 1982 Mar;82(3):507–514. [PubMed] [Google Scholar]
  76. Kremmer T., Wisher M. H., Evans W. H. The lipid composition of plasma membrane subfractions originating from the three major functional domains of the rat hepatocyte cell surface. Biochim Biophys Acta. 1976 Dec 14;455(3):655–664. doi: 10.1016/0005-2736(76)90039-0. [DOI] [PubMed] [Google Scholar]
  77. Kuipers F., Dijkstra T., Havinga R., van Asselt W., Vonk R. J. Acute effects of pentobarbital-anaesthesia on bile secretion. Biochem Pharmacol. 1985 May 15;34(10):1731–1736. doi: 10.1016/0006-2952(85)90642-2. [DOI] [PubMed] [Google Scholar]
  78. LaRusso N. F., Fowler S. Coordinate secretion of acid hydrolases in rat bile. J Clin Invest. 1979 Oct;64(4):948–954. doi: 10.1172/JCI109561. [DOI] [PMC free article] [PubMed] [Google Scholar]
  79. Lange Y., Matthies H. J. Transfer of cholesterol from its site of synthesis to the plasma membrane. J Biol Chem. 1984 Dec 10;259(23):14624–14630. [PubMed] [Google Scholar]
  80. Levine W. G. Biliary excretion of drugs and other xenobiotics. Annu Rev Pharmacol Toxicol. 1978;18:81–96. doi: 10.1146/annurev.pa.18.040178.000501. [DOI] [PubMed] [Google Scholar]
  81. Lowe P. J., Barnwell S. G., Coleman R. Rapid kinetic analysis of the bile-salt-dependent secretion of phospholipid, cholesterol and a plasma-membrane enzyme into bile. Biochem J. 1984 Sep 15;222(3):631–637. doi: 10.1042/bj2220631. [DOI] [PMC free article] [PubMed] [Google Scholar]
  82. Lowe P. J., Coleman R. Fluorescence anisotropy from diphenylhexatriene in rat liver plasma membranes. Biochim Biophys Acta. 1982 Jul 28;689(2):403–409. doi: 10.1016/0005-2736(82)90275-9. [DOI] [PubMed] [Google Scholar]
  83. Lowe P. J., Coleman R. Membrane fluidity and bile salt damage. Biochim Biophys Acta. 1981 Jan 8;640(1):55–65. doi: 10.1016/0005-2736(81)90531-9. [DOI] [PubMed] [Google Scholar]
  84. Lowe P. J., Kan K. S., Barnwell S. G., Sharma R. K., Coleman R. Transcytosis and paracellular movements of horseradish peroxidase across liver parenchymal tissue from blood to bile. Effects of alpha-naphthylisothiocyanate and colchicine. Biochem J. 1985 Jul 15;229(2):529–537. doi: 10.1042/bj2290529. [DOI] [PMC free article] [PubMed] [Google Scholar]
  85. Meier P. J., St Meier-Abt A., Barrett C., Boyer J. L. Mechanisms of taurocholate transport in canalicular and basolateral rat liver plasma membrane vesicles. Evidence for an electrogenic canalicular organic anion carrier. J Biol Chem. 1984 Aug 25;259(16):10614–10622. [PubMed] [Google Scholar]
  86. Meier P. J., Sztul E. S., Reuben A., Boyer J. L. Structural and functional polarity of canalicular and basolateral plasma membrane vesicles isolated in high yield from rat liver. J Cell Biol. 1984 Mar;98(3):991–1000. doi: 10.1083/jcb.98.3.991. [DOI] [PMC free article] [PubMed] [Google Scholar]
  87. Meijer D. K., Keulemans K., Mulder G. J. Isolated perfused rat liver technique. Methods Enzymol. 1981;77:81–94. doi: 10.1016/s0076-6879(81)77013-7. [DOI] [PubMed] [Google Scholar]
  88. Mulder G. J., Scholtens E., Meijer D. K. Collection of metabolites in bile and urine from the rat. Methods Enzymol. 1981;77:21–30. doi: 10.1016/s0076-6879(81)77006-x. [DOI] [PubMed] [Google Scholar]
  89. Mullock B. M., Dobrota M., Hinton R. H. Sources of the proteins of rat bile. Biochim Biophys Acta. 1978 Nov 1;543(4):497–507. doi: 10.1016/0304-4165(78)90304-5. [DOI] [PubMed] [Google Scholar]
  90. Mullock B. M., Hinton R. H., Dobrota M., Peppard J., Orlans E. Distribution of secretory component in hepatocytes and its mode of transfer into bile. Biochem J. 1980 Sep 15;190(3):819–826. doi: 10.1042/bj1900819. [DOI] [PMC free article] [PubMed] [Google Scholar]
  91. Mullock B. M., Jones R. S., Hinton R. H. Movement of endocytic shuttle vesicles from the sinusoidal to the bile canalicular face of hepatocytes does not depend on occupation of receptor sites. FEBS Lett. 1980 May 5;113(2):201–205. doi: 10.1016/0014-5793(80)80591-6. [DOI] [PubMed] [Google Scholar]
  92. Mullock B. M., Jones R. S., Peppard J., Hinton R. H. Effect of colchicine on the transfer of IgA across hepatocytes into bile in isolated perfused rat livers. FEBS Lett. 1980 Nov 3;120(2):278–282. doi: 10.1016/0014-5793(80)80316-4. [DOI] [PubMed] [Google Scholar]
  93. Mullock B. M., Luzio J. P., Hinton R. H. Preparation of a low-density species of endocytic vesicle containing immunoglobulin A. Biochem J. 1983 Sep 15;214(3):823–827. doi: 10.1042/bj2140823. [DOI] [PMC free article] [PubMed] [Google Scholar]
  94. Mullock B. M., Shaw L. J., Fitzharris B., Peppard J., Hamilton M. J., Simpson M. T., Hunt T. M., Hinton R. H. Sources of proteins in human bile. Gut. 1985 May;26(5):500–509. doi: 10.1136/gut.26.5.500. [DOI] [PMC free article] [PubMed] [Google Scholar]
  95. O'Máille E. R., Hofmann A. F. Relatively high biliary secretory maximum for non-micelle-forming bile acid: possible significance for mechanism of secretion. Q J Exp Physiol. 1986 Jul;71(3):475–482. doi: 10.1113/expphysiol.1986.sp003006. [DOI] [PubMed] [Google Scholar]
  96. O'Máille E. R., Richards T. G., Short A. H. The influence of conjugation of cholic acid on its uptake and secretion: hepatic extraction of taurocholate and cholate in the dog. J Physiol. 1967 Apr;189(2):337–350. doi: 10.1113/jphysiol.1967.sp008172. [DOI] [PMC free article] [PubMed] [Google Scholar]
  97. O S. Y., Dupont J. Identification and quantitation of cholanoic acids in hepatic and extra-hepatic tissues of rat. Lipids. 1975 Jun;10(6):340–347. doi: 10.1007/BF02532456. [DOI] [PubMed] [Google Scholar]
  98. Okishio T., Nair P. P. Studies on bile acids. Some observations on the intracellular localization of major bile acids in rat liver. Biochemistry. 1966 Nov;5(11):3662–3668. doi: 10.1021/bi00875a040. [DOI] [PubMed] [Google Scholar]
  99. Oshio C., Phillips M. J. Contractility of bile canaliculi: implications for liver function. Science. 1981 May 29;212(4498):1041–1042. doi: 10.1126/science.7015506. [DOI] [PubMed] [Google Scholar]
  100. Pearson J. P., Kaura R., Taylor W., Allen A. The composition and polymeric structure of mucus glycoprotein from human gallbladder bile. Biochim Biophys Acta. 1982 Sep 7;706(2):221–228. doi: 10.1016/0167-4838(82)90490-3. [DOI] [PubMed] [Google Scholar]
  101. Phillips M. J., Poucell S., Oda M. Mechanisms of cholestasis. Lab Invest. 1986 Jun;54(6):593–608. [PubMed] [Google Scholar]
  102. Rahman K., Coleman R. Selective biliary lipid secretion at low bile-salt-output rates in the isolated perfused rat liver. Effects of phalloidin. Biochem J. 1986 Jul 1;237(1):301–304. doi: 10.1042/bj2370301. [DOI] [PMC free article] [PubMed] [Google Scholar]
  103. Rahman K., Hammond T. G., Lowe P. J., Barnwell S. G., Clark B., Coleman R. Control of biliary phospholipid secretion. Effect of continuous and discontinuous infusion of taurocholate on biliary phospholipid secretion. Biochem J. 1986 Mar 1;234(2):421–427. doi: 10.1042/bj2340421. [DOI] [PMC free article] [PubMed] [Google Scholar]
  104. Reichen J., Paumgartner G. Excretory function of the liver. Int Rev Physiol. 1980;21:103–150. [PubMed] [Google Scholar]
  105. Reichen J., Paumgartner G. Uptake of bile acids by perfused rat liver. Am J Physiol. 1976 Sep;231(3):734–742. doi: 10.1152/ajplegacy.1976.231.3.734. [DOI] [PubMed] [Google Scholar]
  106. Reid L. M., Jefferson D. M. Culturing hepatocytes and other differentiated cells. Hepatology. 1984 May-Jun;4(3):548–559. doi: 10.1002/hep.1840040332. [DOI] [PubMed] [Google Scholar]
  107. Renston R. H., Maloney D. G., Jones A. L., Hradek G. T., Wong K. Y., Goldfine I. D. Bile secretory apparatus: evidence for a vesicular transport mechanism for proteins in the rat, using horseradish peroxidase and [125I]insulin. Gastroenterology. 1980 Jun;78(6):1373–1388. [PubMed] [Google Scholar]
  108. Reuben A., Allen R. M. Intrahepatic sources of biliary-like micelles. Biochim Biophys Acta. 1986 Mar 21;876(1):1–12. doi: 10.1016/0005-2760(86)90311-5. [DOI] [PubMed] [Google Scholar]
  109. Schiff J. M., Fisher M. M., Underdown B. J. Receptor-mediated biliary transport of immunoglobulin A and asialoglycoprotein: sorting and missorting of ligands revealed by two radiolabeling methods. J Cell Biol. 1984 Jan;98(1):79–89. doi: 10.1083/jcb.98.1.79. [DOI] [PMC free article] [PubMed] [Google Scholar]
  110. Simion F. A., Fleischer B., Fleischer S. Subcellular distribution of bile acids, bile salts, and taurocholate binding sites in rat liver. Biochemistry. 1984 Dec 18;23(26):6459–6466. doi: 10.1021/bi00321a028. [DOI] [PubMed] [Google Scholar]
  111. Somjen G. J., Gilat T. A non-micellar mode of cholesterol transport in human bile. FEBS Lett. 1983 Jun 13;156(2):265–268. doi: 10.1016/0014-5793(83)80510-9. [DOI] [PubMed] [Google Scholar]
  112. Stacey N. H., Klaassen C. D. Uptake of galactose, ouabain and taurocholate into centrilobular and periportal enriched hepatocyte subpopulations. J Pharmacol Exp Ther. 1981 Mar;216(3):634–639. [PubMed] [Google Scholar]
  113. Storch J., Schachter D., Inoue M., Wolkoff A. W. Lipid fluidity of hepatocyte plasma membrane subfractions and their differential regulation by calcium. Biochim Biophys Acta. 1983 Jan 5;727(1):209–212. doi: 10.1016/0005-2736(83)90386-3. [DOI] [PubMed] [Google Scholar]
  114. Strange R. C. Hepatic bile salt transport. A review of subcellular binding sites. Biochem Soc Trans. 1981 Feb;9(1):170–174. doi: 10.1042/bst0090170. [DOI] [PubMed] [Google Scholar]
  115. Suchy F. J., Balistreri W. F., Hung J., Miller P., Garfield S. A. Intracellular bile acid transport in rat liver as visualized by electron microscope autoradiography using a bile acid analogue. Am J Physiol. 1983 Nov;245(5 Pt 1):G681–G689. doi: 10.1152/ajpgi.1983.245.5.G681. [DOI] [PubMed] [Google Scholar]
  116. Sugiyama Y., Yamada T., Kaplowitz N. Newly identified bile acid binders in rat liver cytosol. Purification and comparison with glutathione S-transferases. J Biol Chem. 1983 Mar 25;258(6):3602–3607. [PubMed] [Google Scholar]
  117. Sztul E. S., Howell K. E., Palade G. E. Biogenesis of the polymeric IgA receptor in rat hepatocytes. I. Kinetic studies of its intracellular forms. J Cell Biol. 1985 Apr;100(4):1248–1254. doi: 10.1083/jcb.100.4.1248. [DOI] [PMC free article] [PubMed] [Google Scholar]
  118. Sztul E. S., Howell K. E., Palade G. E. Intracellular and transcellular transport of secretory component and albumin in rat hepatocytes. J Cell Biol. 1983 Nov;97(5 Pt 1):1582–1591. doi: 10.1083/jcb.97.5.1582. [DOI] [PMC free article] [PubMed] [Google Scholar]
  119. Sömjen G. J., Gilat T. Changing concepts of cholesterol solubility in bile. Gastroenterology. 1986 Sep;91(3):772–775. doi: 10.1016/0016-5085(86)90652-9. [DOI] [PubMed] [Google Scholar]
  120. Sömjen G. J., Gilat T. Contribution of vesicular and micellar carriers to cholesterol transport in human bile. J Lipid Res. 1985 Jun;26(6):699–704. [PubMed] [Google Scholar]
  121. Sömjen G. J., Marikovsky Y., Lelkes P., Gilat T. Cholesterol-phospholipid vesicles in human bile: an ultrastructural study. Biochim Biophys Acta. 1986 Oct 24;879(1):14–21. doi: 10.1016/0005-2760(86)90260-2. [DOI] [PubMed] [Google Scholar]
  122. Takahashi I., Nakane P. K., Brown W. R. Ultrastructural events in the translocation of polymeric IgA by rat hepatocytes. J Immunol. 1982 Mar;128(3):1181–1187. [PubMed] [Google Scholar]
  123. Thomas P., O'Neil P. F., Zamcheck N. The effects of colchicine and vinblastine on the biliary excretion of carcinoembryonic antigen. Hepatology. 1985 Mar-Apr;5(2):207–210. doi: 10.1002/hep.1840050208. [DOI] [PubMed] [Google Scholar]
  124. Thomas P., Toth C. A., Zamcheck N. The mechanism of biliary excretion of alpha 1-acid glycoprotein in the rat: evidence for a molecular weight-dependent, nonreceptor-mediated pathway. Hepatology. 1982 Nov-Dec;2(6):800–803. doi: 10.1002/hep.1840020610. [DOI] [PubMed] [Google Scholar]
  125. Thurman R. G., Kauffman F. C. Sublobular compartmentation of pharmacologic events (SCOPE): metabolic fluxes in periportal and pericentral regions of the liver lobule. Hepatology. 1985 Jan-Feb;5(1):144–151. doi: 10.1002/hep.1840050128. [DOI] [PubMed] [Google Scholar]
  126. Tuchweber B., Weber A., Roy C. C., Yousef I. M. Mechanisms of experimentally induced intrahepatic cholestasis. Prog Liver Dis. 1986;8:161–178. [PubMed] [Google Scholar]
  127. Van Dyke R. W., Stephens J. E., Scharschmidt B. F. Bile acid transport in cultured rat hepatocytes. Am J Physiol. 1982 Dec;243(6):G484–G492. doi: 10.1152/ajpgi.1982.243.6.G484. [DOI] [PubMed] [Google Scholar]
  128. Wheeler H. O., King K. K. Biliary excretion of lecithin and cholesterol in the dog. J Clin Invest. 1972 Jun;51(6):1337–1350. doi: 10.1172/JCI106930. [DOI] [PMC free article] [PubMed] [Google Scholar]
  129. Whetton A. D., Houslay M. D., Dodd N. J., Evans W. H. The lipid fluidity of rat liver membrane subfractions. Biochem J. 1983 Sep 15;214(3):851–854. doi: 10.1042/bj2140851. [DOI] [PMC free article] [PubMed] [Google Scholar]
  130. Yousef I. M., Barnwell S., Gratton F., Tuchweber B., Weber A., Roy C. C. Liver cell membrane solubilization may control maximum secretory rate of cholic acid in the rat. Am J Physiol. 1987 Jan;252(1 Pt 1):G84–G91. doi: 10.1152/ajpgi.1987.252.1.G84. [DOI] [PubMed] [Google Scholar]
  131. Yousef I. M., Fisher M. M. In vitro effect of free bile acids on the bile canalicular membrane phospholipids in the rat. Can J Biochem. 1976 Dec;54(12):1040–1046. doi: 10.1139/o76-152. [DOI] [PubMed] [Google Scholar]
  132. von Dippe P., Drain P., Levy D. Synthesis and transport characteristics of photoaffinity probes for the hepatocyte bile acid transport system. J Biol Chem. 1983 Jul 25;258(14):8890–8895. [PubMed] [Google Scholar]

Articles from Biochemical Journal are provided here courtesy of The Biochemical Society

RESOURCES