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. 1987 Jun 1;244(2):311–315. doi: 10.1042/bj2440311

Rapid subcellular fractionation of the rat liver endocytic compartments involved in transcytosis of polymeric immunoglobulin A and endocytosis of asialofetuin.

W J Branch 1, B M Mullock 1, J P Luzio 1
PMCID: PMC1147992  PMID: 2444213

Abstract

The distributions of two endocytosed radiolabelled ligands (polymeric immunoglobulin A and asialofetuin) in rat liver endocytic compartments were investigated by using rapid subcellular fractionation of post-mitochondrial supernatants on vertical density gradients of Ficoll or Nycodenz. Two endocytic compartments were identified, both ligands being initially associated with a light endocytic-vesicle fraction on Ficoll gradients, asialofetuin then accumulating in denser endosomes before transfer to lysosomes for degradation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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