Abstract
Two endogenous differentiation-inducing factors (DIF-2 and DIF-3), which induce stalk-cell differentiation in the cellular slime mould Dictyostelium discoideum, have been identified as the pentan-1-one and monochloro analogues respectively of (1-[(3,5-dichloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one). These compounds represent a new chemical class of effector molecules.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Brookman J. J., Jermyn K. A., Kay R. R. Nature and distribution of the morphogen DIF in the Dictyostelium slug. Development. 1987 May;100(1):119–124. doi: 10.1242/dev.100.1.119. [DOI] [PubMed] [Google Scholar]
- Brookman J. J., Town C. D., Jermyn K. A., Kay R. R. Developmental regulation of a stalk cell differentiation-inducing factor in Dictyostelium discoideum. Dev Biol. 1982 May;91(1):191–196. doi: 10.1016/0012-1606(82)90022-7. [DOI] [PubMed] [Google Scholar]
- Kay R. R., Dhokia B., Jermyn K. A. Purification of stalk-cell-inducing morphogens from Dictyostelium discoideum. Eur J Biochem. 1983 Oct 17;136(1):51–56. doi: 10.1111/j.1432-1033.1983.tb07703.x. [DOI] [PubMed] [Google Scholar]
- Morris H. R., Taylor G. W., Masento M. S., Jermyn K. A., Kay R. R. Chemical structure of the morphogen differentiation inducing factor from Dictyostelium discoideum. 1987 Aug 27-Sep 2Nature. 328(6133):811–814. doi: 10.1038/328811a0. [DOI] [PubMed] [Google Scholar]
- Siuda J. F., DeBernardis J. F. Naturally occurring halogenated organic compounds. Lloydia. 1973 Jun;36(2):107–143. [PubMed] [Google Scholar]
- Town C. D., Gross J. D., Kay R. R. Cell differentiation without morphogenesis in Dictyostelium discoideum. Nature. 1976 Aug 19;262(5570):717–719. doi: 10.1038/262717a0. [DOI] [PubMed] [Google Scholar]
- Town C., Stanford E. An oligosaccharide-containing factor that induces cell differentiation in Dictyostelium discoideum. Proc Natl Acad Sci U S A. 1979 Jan;76(1):308–312. doi: 10.1073/pnas.76.1.308. [DOI] [PMC free article] [PubMed] [Google Scholar]