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. 2024 Jul 6;46(6):6395–6417. doi: 10.1007/s11357-024-01264-3

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© The Author(s), under exclusive licence to American Aging Association 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

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Fig. 2 — Comparison of top 21 canonical pathways in aged rhesus macaques and aged olive baboons. Rhesus macaques (cyan) and olive baboons (yellow) activation Z-scores (an inferred measurement of the pathway activation stated based on measured levels and IPA knowledge) is shown by bubble position on the X-axis, pathway names in the Y-axis, where p-values are represented by bubble size. Highly overlapping pathways were removed from analysis and only the most comprehensive pathway is displayed. Enriched pathways in both rhesus macaques and olive baboons are underlined in red (increased activation), blue (reduced activation), or grey (divergent)