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. 2024 Apr 19;108(11):2197–2208. doi: 10.1097/TP.0000000000005002

TABLE 4.

NRP permissibility under variable death determination frameworks

Death in DCDD based on Criteria met under current DCDD protocols Criteria met under current DCDD-NRP protocols
Cessation of circulation
 Permanent Yes No
 Irreversible No No
Cessation of intracranial circulation
 Permanent Yes Yesa
 Irreversible No No
Cessation of brain function
 Permanent Yes Yesa
 Irreversible No Nob
a

Under condition that brain function has ceased at the time NRP is initiated and that surgical safeguards are effective.

b

Could be permissible provided brain function is irreversibly lost, but not permissible under current protocols because NRP is initiated prior.

DCDD, donation after circulatory determination of death; NRP, normothermic regional perfusion.