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. 1990 Dec 15;272(3):627–631. doi: 10.1042/bj2720627

Cloning, sequencing and analysis of the structural gene and regulatory region of the Pseudomonas aeruginosa chromosomal ampC beta-lactamase.

J M Lodge 1, S D Minchin 1, L J Piddock 1, J W Busby 1
PMCID: PMC1149754  PMID: 2125210

Abstract

The chromosomal gene from Pseudomonas aeruginosa encoding beta-lactamase has been cloned, and the sequence determined and compared with corresponding sequences of beta-lactamases from members of the enterobacteriaceae. Upstream of the beta-lactamase gene is an open reading frame which we postulate encodes a regulatory protein, AmpR. We identified a helix-turn-helix region in AmpR and a putative AmpR-binding site.

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Selected References

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