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. 1991 Nov 1;279(Pt 3):903–906. doi: 10.1042/bj2790903

Aldehyde reductase is a major protein associated with 3-deoxyglucosone reductase activity in rat, pig and human livers.

T Kanazu 1, M Shinoda 1, T Nakayama 1, Y Deyashiki 1, A Hara 1, H Sawada 1
PMCID: PMC1151532  PMID: 1953687

Abstract

3-Deoxyglucosone reductase activity in the extracts of rat, pig and human livers was potently inhibited by aldehyde reductase inhibitors. The major species of 3-deoxyglucosone reductase purified from human and pig livers were biochemically and immunochemically identical with aldehyde reductase. The two enzymes and rat liver aldehyde reductase exhibited higher catalytic efficiency for 3-deoxyglucosone than for D-glucuronate, a representative substrate of aldehyde reductase.

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Selected References

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