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. 1983 Sep 15;214(3):1023–1025. doi: 10.1042/bj2141023

Desmosine and isodesmosine contents and elastase activity in normal and cirrhotic rat liver.

V Velebný, E Kasafírek, J Kanta
PMCID: PMC1152350  PMID: 6556069

Abstract

The contents of desmosine and isodesmosine, the cross-linking amino acids of elastin, were increased 4-fold in rat liver with carbon tetrachloride-induced cirrhosis, which suggests that insoluble elastin accumulates in cirrhosis. Elastase activity in the cirrhotic liver, as determined with 3-carboxypropionyl-L-alanyl-L-alanyl-L-alanine p-nitroanilide, was 17% less than in the normal liver; no change was found when Congo Red-elastin was used as a substrate.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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