Abstract
Starch-gel electrophoresis was used to demonstrate two forms of glutathione S-transferase in human erythrocytes. Whereas considerable inter-individual differences in enzyme activity and electrophoretic patterns were detected, intra-individual differences were small.
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- Chasseaud L. F. The role of glutathione and glutathione S-transferases in the metabolism of chemical carcinogens and other electrophilic agents. Adv Cancer Res. 1979;29:175–274. doi: 10.1016/s0065-230x(08)60848-9. [DOI] [PubMed] [Google Scholar]
- Hopkinson D. A., Harris H. The investigation of reactive sulphydryls in enzymes and their variants by starch gel electrophoresis. Studies on red cell adenosine deaminase. Ann Hum Genet. 1969 Jul;33(1):81–87. doi: 10.1111/j.1469-1809.1969.tb01632.x. [DOI] [PubMed] [Google Scholar]
- Marcus C. J., Habig W. H., Jakoby W. B. Glutathione transferase from human erythrocytes. Nonidentity with the enzymes from liver. Arch Biochem Biophys. 1978 Jun;188(2):287–293. doi: 10.1016/s0003-9861(78)80011-3. [DOI] [PubMed] [Google Scholar]
- Nebert D. W. The Ah locus. A gene with possible importance in cancer predictability. Arch Toxicol Suppl. 1980;3:195–207. doi: 10.1007/978-3-642-67389-4_14. [DOI] [PubMed] [Google Scholar]
- Scott E. M., Wright R. C. Variability of glutathione S-transferase of human erythrocytes. Am J Hum Genet. 1980 Jan;32(1):115–117. [PMC free article] [PubMed] [Google Scholar]
- Strange R. C., Johnson P. H., Lawton A., Moult J. A., Tector M. J., Tyminski R. J., Cotton W. Studies on the variability of glutathione S-transferase from human erythrocytes. Clin Chim Acta. 1982 Apr 8;120(2):251–260. doi: 10.1016/0009-8981(82)90162-0. [DOI] [PubMed] [Google Scholar]
- Strange R. C., Johnston J. D., Coghill D. R., Hume R. A comparison of erythrocyte glutathione S-transferase activity from human foetuses and adults. Biochem J. 1980 May 15;188(2):475–479. doi: 10.1042/bj1880475. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wurzinger K. H., Mohrenweiser H. W. Studies on the genetic and non-genetic (physiological) variation of human erythrocyte glutamic oxaloacetic transaminase. Ann Hum Genet. 1982 Jul;46(Pt 3):191–201. doi: 10.1111/j.1469-1809.1982.tb00711.x. [DOI] [PubMed] [Google Scholar]