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. 1985 Aug 15;230(1):277–280. doi: 10.1042/bj2300277

Seminalplasmin. An endogenous calmodulin antagonist.

K Gietzen, H J Galla
PMCID: PMC1152613  PMID: 2996494

Abstract

Seminalplasmin, a strongly basic protein isolated from bull semen, was found to antagonize with high potency and extraordinary specificity the function of calmodulin. Calmodulin antagonism is the result of an interaction between the two proteins, which is mainly determined by electrostatic forces. The stimulation of Ca2+-transporting ATPase and phosphodiesterase by calmodulin was half-maximally inhibited at approx. 0.1 microM-seminalplasmin. However, the basal activity of calmodulin-dependent enzymes was not significantly altered by seminalplasmin over the concentration range investigated.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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