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Cellular and Molecular Neurobiology logoLink to Cellular and Molecular Neurobiology
. 2002 Apr;22(2):191–195. doi: 10.1023/A:1019817906139

Increased Synaptophysin Expression Through Whisker Stimulation in Rat

Hidetoshi Ishibashi 1
PMCID: PMC11533744  PMID: 12363201

Abstract

1. Synaptophysin is responsible for the cycling of the synaptic vesicles containing the neurotransmitter, and it can be phosphorylated.

2. This study examined whether repeated whisker stimulation alters the expression of synaptophysin mRNA in the rat barrel cortex, and found induced expression of synaptophysin mRNA in the contralateral barrel cortex compared to that in the ipsilateral hemisphere.

3. This result suggests that synaptophysin is involved in the modulation of the synaptic plasticity.

Keywords: whisker, barrel cortex, plasticity, synaptic transmission, synaptophysin

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