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. 1982 Dec 1;207(3):583–587. doi: 10.1042/bj2070583

Haem disorder in reconstituted human haemoglobin

John C Docherty 1, Stanley B Brown 1
PMCID: PMC1153901  PMID: 7165711

Abstract

Degradation of the haem of haemoglobin (used as a chemical probe of the haem–protein relationship), suggests that reconstituted human haemoglobin contains significant haem disorder. This results from the insertion of haem into globin with an orientation 180° different from the natural orientation. Haem disorder also slowly occurs in methaemoglobin solutions.

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Selected References

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