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. 1982 Dec 15;208(3):819–822. doi: 10.1042/bj2080819

The effect of adrenalectomy on GDP binding to brown-adipose-tissue mitochondria of obese rats

Susan Holt 1, David A York 1,*
PMCID: PMC1154036  PMID: 7165736

Abstract

GDP binding to brown-adipose-tissue mitochondria of young obese Zucker rats (fa/fa) was significantly lower than in lean control rats, as a result of a decrease in the number of binding sites. Adrenalectomy of fa/fa rats restored GDP binding to control values. Corticosterone replacement suppressed GDP binding in adrenalectomized obese rats.

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Selected References

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