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. 1982 Dec 15;208(3):823–830. doi: 10.1042/bj2080823

Cystine accumulation in cystinotic fibroblasts from free and protein-linked cystine but not cysteine

Jess G Thoene 1, Rosemary M Lemons 1
PMCID: PMC1154037  PMID: 6762213

Abstract

The accumulation of cystine in cystinotic fibroblasts from free and protein-linked cystine has been investigated. Cystine is not accumulated from cysteine but is readily accumulated from cystine. The accumulation from free cystine does not occur as a result of pinocytosis or from the degradation of a rapidly metabolized protein pool. Further studies of the degradation of disulphide-containing proteins by these cells may aid understanding of the mechanisms of proteolysis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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