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Prevention and protection of marine-derived fucose-containing carbohydrates on inflammatory injuries. FCCs ameliorate peptic ulcers and IBD through modulation of cytokines, protective mediators, leukocyte migration, balance between oxidative reactions and antioxidant defenses, and tight junctions. PGE2, prostaglandin E2; EGF, epidermal growth factor; EGFR, epidermal growth factor receptor; ROS, reactive oxygen species; RNS, reactive nitrogen species.
