Figure 2.

Capsaicin (CAPS) reduces proliferation of cisplatin-resistant malignant mesothelioma (MM) cell lines. Cisplatin-resistant MSTO-211H (a) and NCI-H2052 (b) cells were treated with RPMI 1640 medium alone (RPMI); medium containing DMSO (DMSO) at the same %v/v as CAPS concentration; medium containing CAPS at a concentration of 200 µM (CAPS 200) for 24, 48 and 72 h. Data are expressed as percentage of growth increase over time 0 and represent results obtained by two independent experiments performed in triplicate. Statistical differences were evaluated by one-way analysis of variance (ANOVA) (* p-value < 0.05, ** p-value < 0.01 versus DMSO).