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(a) The absorbance and time relationship for the Hem1 aptamer complex with six different cofactor environments. The sodium and magnesium pairing vastly increases activity to roughly double PS2.M’s highest activity with any cofactors. (b) The absorbance and time relationship for PS2.M aptamer complex with six different cofactor environments. Potassium shows the most promising results but remains at roughly 0.3 a.u. Adapted from Ref. [135] with permission.
