Table 1.

Experimental conditions for the metabolic reactions.

CYP variants	CYP concentration nmol P450/mL	Substrate	Substrate concentration μM	Incubation time min
2C9
.1, .2				30
	0.008	Warfarin	0, 1, 3, 10, 30, 100, 300
.3				90
2C19
.1A, .1B, .10, .23			0, 0.3, 1, 3, 10, 30
	0.005	Omeprazole		10
.8			0, 1, 3, 10, 30, 50
3A4
.1, .2, .7, .16, .18	0.0125	Midazolam	0, 0.5, 1, 3, 10, 30, 50	5