In the article “INFORM: INFrared-based ORganizational Measurements of tumor and its microenvironment to predict patient survival” two key authors, who provided the tissue microarray tumor samples and related patient and histopathological data, were not included in the published version of the research paper. Therefore, with the agreement of all the involved authors, Karin Jirstrom and Helgi Birgisson, were added to the list of authors.
Additionally, Fig. 3 was updated to fix the plotting in panel C and a mistake in panel D. In panel C, the lines close to the origin were obscured by the axes, thus not clearly displaying the earliest part of the curve. This has now been corrected. The plotting in panel D has been corrected to reflect the commonly understood definition of disease-free survival.
The following text relating to Fig. 3 has also been updated. The original “In addition, the Kaplan-Meier survival curves for overall survival and disease-free survival showed significantly different outcomes for patients stratified with dichotomized IRS scores (Fig. 3, C and D) with P values of 0.0003 and 0.0274 and at powers 0.93 and 0.40, respectively. Although IRS shows significant patient stratification in determining disease-free survival in univariate analysis, our dataset is not powered for predicting disease-free survival. Given the low power in the current dataset to determine recurrence, it is unclear whether IRS is predictive of disease-free survival.” was corrected to read “In addition, the Kaplan-Meier survival curves for overall survival and disease-free survival showed significantly different outcomes for patients stratified with dichotomized IRS scores (Fig. 3, C and D) with P values of 0.0003 and 0.0005 and at powers 0.93 and 0.92, respectively. Our results indicate that IRS shows significant patient stratification in determining both overall and disease-free survival.”
Lastly, the authors added this text to the “Imaging” section of the Materials and Methods: “The study was approved by the Regional Ethics Committee in Uppsala, Sweden (Dnr. 2000:001 and Dnr. 2009:345). Written study information was given to the patients, and all patients participating in the study gave a verbal consent. The verbal consent was approved by the ethical committee and was documented in a questionnaire filled in by the patient or the researcher.”
The HTML and PDF versions of the paper have been corrected.