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. 1982 Jan 15;202(1):249–254. doi: 10.1042/bj2020249

Monensin inhibits synthesis of proteoglycan, but not of hyaluronate, in chondrocytes

Diane Mitchell 1,*, Tim Hardingham 1
PMCID: PMC1158098  PMID: 6805469

Abstract

Monensin (10nm–1μm) inhibited the incorporation of [35S]sulphate and [3H]glucosamine into proteoglycans by rat chondrosarcoma cells, but the incorporation of [3H]glucosamine into hyaluronate was unaffected. The results suggest that hyaluronate synthesis occurs in a cell compartment separate from chondroitin sulphate synthesis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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