Abstract
1. Chronic HCl acidosis was induced in dogs. 2. Hepatic extraction of glutamine fell compared with normal animals. 3. Muscle glutamine production was unchanged in acidosis. 4. The results are discussed in relation to inter-organ glutamine metabolism in acidosis in vivo.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Baverel G., Lund P. A role for bicarbonate in the regulation of mammalian glutamine metabolism. Biochem J. 1979 Dec 15;184(3):599–606. doi: 10.1042/bj1840599. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Heinz E., Pichler A. G., Pfeiffer B. Studies on the transport of glutamate in Ehrlich cells--inhibition by other amino acids and stimulation by H-ions. Biochem Z. 1965 Sep 30;342(5):542–552. [PubMed] [Google Scholar]
- Lueck J. D., Miller L. L. The effect of perfusate pH on glutamine metabolism in the isolated perfused rat liver. J Biol Chem. 1970 Oct 25;245(20):5491–5497. [PubMed] [Google Scholar]
- PITTS R. F. RENAL PRODUCTION AND EXCRETION OF AMMONIA. Am J Med. 1964 May;36:720–742. doi: 10.1016/0002-9343(64)90182-2. [DOI] [PubMed] [Google Scholar]
- Pitts R. F., Pilkington L. A., MacLeod M. B., Leal-Pinto E. Metabolism of glutamine by the intact functioning kidney of the dog. Studies in metabolic acidosis and alkalosis. J Clin Invest. 1972 Mar;51(3):557–565. doi: 10.1172/JCI106844. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ruderman N. B., Berger M. The formation of glutamine and alanine in skeletal muscle. J Biol Chem. 1974 Sep 10;249(17):5500–5506. [PubMed] [Google Scholar]
- Schröck H., Cha C. J., Goldstein L. Glutamine release from hindlimb and uptake by kidney in the acutely acidotic rat. Biochem J. 1980 May 15;188(2):557–560. doi: 10.1042/bj1880557. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Schröck H., Goldstein L. Interorgan relationships for glutamine metabolism in normal and acidotic rats. Am J Physiol. 1981 May;240(5):E519–E525. doi: 10.1152/ajpendo.1981.240.5.E519. [DOI] [PubMed] [Google Scholar]
- Windmueller H. G., Spaeth A. E. Identification of ketone bodies and glutamine as the major respiratory fuels in vivo for postabsorptive rat small intestine. J Biol Chem. 1978 Jan 10;253(1):69–76. [PubMed] [Google Scholar]