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. 1982 Apr 1;203(1):335–338. doi: 10.1042/bj2030335

Impaired degradation of keratan sulphate by Morquio A fibroblasts.

J Glössl, H Kresse
PMCID: PMC1158229  PMID: 6213226

Abstract

Upon incubation of keratan [35S]sulphate with normal fibroblasts both [35S]sulphate and N-acetylglucosamine 6-[35S]sulphate are liberated. From the products obtained after digestion with various mutant fibroblasts and with purified N-acetylgalactosamine 6-sulphate sulphatase we suggest that (i) [35S]sulphate is released almost exclusively from galactose 6-sulphate residues; (ii) N-acetylgalactosamine 6-sulphate sulphatase exhibits galactose 6-sulphate sulphatase activity; (iii) both sulphatase activities are deficient in Morquio disease type A.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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