Correction to “Iridium-Catalyzed Enantioselective Propargylic C–H Trifluoromethylthiolation and Related Processes”

Due to errors in data transcription, incorrect reaction conditions and yields were displayed in Table 1 and Scheme 2 of the manuscript and in the Supporting Information. In addition, the procedure for a 5 mmol scale reaction was inadvertently left out of the Supporting Information. The corrected Table and Scheme are displayed below, and the Supporting Information has been updated with a revised version. We regret any inconvenience caused by these errors and omissions.

Table 1. Screening of Reaction Conditions^a.

			Yield (%)
Entry	[SCF3]+	Lewis acid	2a	2a′	2a″	ee (%)
1	R1	BF3·Et2O	0
2	R2	BF3·Et2O	7
3	R3	BF3·Et2O	1
4	R4	BF3·Et2O	0
5b	R2	Me3SiOTf	67	32	0	98
6b	R2	Et3SiOTf	78	20	0	98
7b	R2	iPr3SiOTf	58	0	41	96
8b	R2	iPrEt2SiOTf	31	7	13
9b	R5	Et3SiOTf	95	0	0	96
10b	R6	Et3SiOTf	98	0	0	97
11c	R6	Et3SiOTf	93	0	0	97

^aYields were determined by ¹H NMR spectroscopy using 1,3,5-trimethoxybenzene as the internal standard, TMPH = 2,2,6,6-tetramethylpiperidine.

^b35 °C.

^c[Ir(cod)Cl]₂ (2 mol %, 4 mol % Ir), (S)-L (8 mol %), 1a (1.0 equiv), R6 (1.5 equiv), TMPH (2.0 equiv) and TESOTf (1.25 equiv), DCE [1.0 M], r.t., overnight.

Scheme 2. Synthetic Utility.

Standard conditions.

DCE [0.5 M].

See the Supporting Information.

Supporting Information Available

The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/jacs.4c13920.

• Experimental procedures, characterization of new compounds, X-ray crystallographic data, copies of NMR spectra, and copies of HPLC traces (PDF)