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. 1982 Sep 15;206(3):671–674. doi: 10.1042/bj2060671

Sendai virus causes a rise in intracellular free Ca2+ before cell fusion

Maurice B Hallett *, Pinhas Fuchs , Anthony K Campbell *
PMCID: PMC1158639  PMID: 6293470

Abstract

1. Sendai virus caused a large increase in the concentration of free Ca2+ within human erythrocyte ghosts detected by the Ca2+-activated photoprotein obelin. 2. The increase in intracellular [Ca2+] preceded fusion. However, fusion could also be observed in the absence of a detectable rise in intracellular free [Ca2+]. 3. It was concluded that the increase in intracellular free [Ca2+] was not an absolute requirement for cell fusion, but may be necessary to produce fusion at the maximum rate.

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Selected References

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