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. 1980 Feb 15;186(2):621–624. doi: 10.1042/bj1860621

Interactions between vasopressin and glucagon on ketogenesis and oleate metabolism in isolated hepatocytes from fed rats.

D H Williamson, V Ilic, A F Tordoff, E V Ellington
PMCID: PMC1161618  PMID: 7378069

Abstract

Vasopressin (10nM) inhibited ketogenesis (56%) in hepatocytes from fed rats when oleate (1 mM) was the substrate, but had no effect with butyrate (10mM). The hormone increased the accumulation of lactate and stimulated the esterification of [1(-14)C]oleate (70%). These effects of vasopressin were reversed by glucagon (10 nM). The physiological implications of these findings are discussed.

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Selected References

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