Abstract
Direct computer-based physician order entry has been the subject of debate for over 20 years. Many sites have implemented systems successfully. Others have failed outright or flirted with disaster, incurring substantial delays, cost overruns, and threatened work actions. The rationale for physician order entry includes process improvement, support of cost-conscious decision making, clinical decision support, and optimization of physicians' time. Barriers to physician order entry result from the changes required in practice patterns, roles within the care team, teaching patterns, and institutional policies. Key ingredients for successful implementation include: the system must be fast and easy to use, the user interface must behave consistently in all situations, the institution must have broad and committed involvement and direction by clinicians prior to implementation, the top leadership of the organization must be committed to the project, and a group of problem solvers and users must meet regularly to work out procedural issues. This article reviews the peer-reviewed scientific literature to present the current state of the art of computer-based physician order entry.
Full Text
The Full Text of this article is available as a PDF (1.9 MB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Allen S. I., Johannes R. S., Brown C. S., Kafonek D. M., Plexico P. S. Prescription-writing with a PC. Comput Methods Programs Biomed. 1986 Mar;22(1):127–135. doi: 10.1016/0169-2607(86)90102-1. [DOI] [PubMed] [Google Scholar]
- Anderson J. G., Jay S. J., Perry J., Anderson M. M., Schweer H. M. Informal communication networks and change in physicians' practice behavior. Res Med Educ. 1988;27:127–132. [PubMed] [Google Scholar]
- Barnett G. O., Cimino J. J., Hupp J. A., Hoffer E. P. DXplain. An evolving diagnostic decision-support system. JAMA. 1987 Jul 3;258(1):67–74. doi: 10.1001/jama.258.1.67. [DOI] [PubMed] [Google Scholar]
- Brown C. S., Allen S. I., Songco D. C. A computerized prescription writing program for doctors. Methods Inf Med. 1985 Apr;24(2):101–105. [PubMed] [Google Scholar]
- Collen M. F. General requirements for a Medical Information System (MIS). Comput Biomed Res. 1970 Oct 5;3(5):393–406. doi: 10.1016/0010-4809(70)90001-7. [DOI] [PubMed] [Google Scholar]
- Dambro M. R., Weiss B. D., McClure C. L., Vuturo A. F. An unsuccessful experience with computerized medical records in an academic medical center. J Med Educ. 1988 Aug;63(8):617–623. doi: 10.1097/00001888-198808000-00005. [DOI] [PubMed] [Google Scholar]
- Dasta J. F., Greer M. L., Speedie S. M. Computers in healthcare: overview and bibliography. Ann Pharmacother. 1992 Jan;26(1):109–117. doi: 10.1177/106002809202600120. [DOI] [PubMed] [Google Scholar]
- Donald J. B. On line prescribing by computer. Br Med J (Clin Res Ed) 1986 Apr 5;292(6525):937–939. doi: 10.1136/bmj.292.6525.937. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Doskocil M., Med M., Vimmer T. Musculus rectus femoris--zacátecní slacha, její funkcní význam. Acta Chir Orthop Traumatol Cech. 1987 Apr;54(2):99–107. [PubMed] [Google Scholar]
- East T. D., Morris A. H., Wallace C. J., Clemmer T. P., Orme J. F., Jr, Weaver L. K., Henderson S., Sittig D. F. A strategy for development of computerized critical care decision support systems. Int J Clin Monit Comput. 1991;8(4):263–269. doi: 10.1007/BF01739127. [DOI] [PubMed] [Google Scholar]
- Ellinoy B. J. Fax fiction. Am J Hosp Pharm. 1989 Aug;46(8):1549–1550. [PubMed] [Google Scholar]
- Evans R. S., Pestotnik S. L., Burke J. P., Gardner R. M., Larsen R. A., Classen D. C. Reducing the duration of prophylactic antibiotic use through computer monitoring of surgical patients. DICP. 1990 Apr;24(4):351–354. doi: 10.1177/106002809002400401. [DOI] [PubMed] [Google Scholar]
- Gardner R. M., Golubjatnikov O. K., Laub R. M., Jacobson J. T., Evans R. S. Computer-critiqued blood ordering using the HELP system. Comput Biomed Res. 1990 Dec;23(6):514–528. doi: 10.1016/0010-4809(90)90038-e. [DOI] [PubMed] [Google Scholar]
- Garrett L. E., Jr, Hammond W. E., Stead W. W. The effects of computerized medical records on provider efficiency and quality of care. Methods Inf Med. 1986 Jul;25(3):151–157. [PubMed] [Google Scholar]
- Glaser J. P., Teich J., Kuperman G. The future of clinical information systems: one hospital's perspective. Top Health Inf Manage. 1993 Aug;14(1):12–24. [PubMed] [Google Scholar]
- Goldberg D. E., Baardsgaard G., Johnson M. T., Jolowsky C. M., Shepherd M., Peterson C. D. Computer-based program for identifying medication orders requiring dosage modification based on renal function. Am J Hosp Pharm. 1991 Sep;48(9):1965–1969. [PubMed] [Google Scholar]
- Gouveia W. A. Managing pharmacy information systems. Am J Hosp Pharm. 1993 Jan;50(1):113–116. [PubMed] [Google Scholar]
- Greenes R. A., Tarabar D. B., Krauss M., Anderson G., Wolnik W. J., Cope L., Slosser E., Hersh W. Knowledge management as a decision support method: a diagnostic workup strategy application. Comput Biomed Res. 1989 Apr;22(2):113–135. doi: 10.1016/0010-4809(89)90021-9. [DOI] [PubMed] [Google Scholar]
- Halpern N. A., Thompson R. E., Greenstein R. J. A computerized intensive care unit order-writing protocol. Ann Pharmacother. 1992 Feb;26(2):251–254. doi: 10.1177/106002809202600222. [DOI] [PubMed] [Google Scholar]
- Haynes R. B., McKibbon K. A., Walker C. J., Ryan N., Fitzgerald D., Ramsden M. F. Online access to MEDLINE in clinical settings. A study of use and usefulness. Ann Intern Med. 1990 Jan 1;112(1):78–84. doi: 10.7326/0003-4819-112-1-78. [DOI] [PubMed] [Google Scholar]
- Kahn C. E., Jr, Kovatsis P. G., Messersmith R. N., Lehr J. L. Automated entry of radiology requisition information with artificial-intelligence techniques. AJR Am J Roentgenol. 1989 Nov;153(5):1085–1088. doi: 10.2214/ajr.153.5.1085. [DOI] [PubMed] [Google Scholar]
- Kahn C. E., Jr, Messersmith R. N., Jokich M. D. PHOENIX. An expert system for selecting diagnostic imaging procedures. Invest Radiol. 1987 Dec;22(12):978–980. [PubMed] [Google Scholar]
- Kawahara N. E., Jordan F. M. Influencing prescribing behavior by adapting computerized order-entry pathways. Am J Hosp Pharm. 1989 Sep;46(9):1798–1801. [PubMed] [Google Scholar]
- Kingsland L. C., 3rd, Harbourt A. M., Syed E. J., Schuyler P. L. Coach: applying UMLS knowledge sources in an expert searcher environment. Bull Med Libr Assoc. 1993 Apr;81(2):178–183. [PMC free article] [PubMed] [Google Scholar]
- Klatt E. C. Voice-activated dictation for autopsy pathology. Comput Biol Med. 1991;21(6):429–433. doi: 10.1016/0010-4825(91)90044-a. [DOI] [PubMed] [Google Scholar]
- Larson R. L., Blake J. P. Achieving order entry by physicians in a computerized medical record. Hosp Pharm. 1988 Jun;23(6):551–553. [PubMed] [Google Scholar]
- Lehr J. L., Lodwick G. S., Nicholson B. F., Birznieks F. B. Experience with MARS (Missouri Automated Radiology System). Radiology. 1973 Feb;106(2):289–294. doi: 10.1148/106.2.289. [DOI] [PubMed] [Google Scholar]
- Lepage E. F., Gardner R. M., Laub R. M., Golubjatnikov O. K. Improving blood transfusion practice: role of a computerized hospital information system. Transfusion. 1992 Mar-Apr;32(3):253–259. doi: 10.1046/j.1537-2995.1992.32392213810.x. [DOI] [PubMed] [Google Scholar]
- Levit F., Garside D. B. Computer-assisted prescription writing. Comput Biomed Res. 1977 Oct;10(5):501–510. doi: 10.1016/0010-4809(77)90024-6. [DOI] [PubMed] [Google Scholar]
- Massaro T. A. Introducing physician order entry at a major academic medical center: I. Impact on organizational culture and behavior. Acad Med. 1993 Jan;68(1):20–25. doi: 10.1097/00001888-199301000-00003. [DOI] [PubMed] [Google Scholar]
- Massaro T. A. Introducing physician order entry at a major academic medical center: II. Impact on medical education. Acad Med. 1993 Jan;68(1):25–30. doi: 10.1097/00001888-199301000-00004. [DOI] [PubMed] [Google Scholar]
- McAllister J. C., 3rd Pharmacy fax. Am J Hosp Pharm. 1989 Feb;46(2):255–256. [PubMed] [Google Scholar]
- McDonald C. J. Protocol-based computer reminders, the quality of care and the non-perfectability of man. N Engl J Med. 1976 Dec 9;295(24):1351–1355. doi: 10.1056/NEJM197612092952405. [DOI] [PubMed] [Google Scholar]
- McDonald C. J., Tierney W. M. The Medical Gopher--a microcomputer system to help find, organize and decide about patient data. West J Med. 1986 Dec;145(6):823–829. [PMC free article] [PubMed] [Google Scholar]
- Meth R. J. Methods of determining blood pressure. West J Med. 1985 Jan;142(1):101–101. [PMC free article] [PubMed] [Google Scholar]
- Miller R., Masarie F. E., Myers J. D. Quick medical reference (QMR) for diagnostic assistance. MD Comput. 1986 Sep-Oct;3(5):34–48. [PubMed] [Google Scholar]
- Ogura H., Sagara E., Iwata M., Nishioka Y., Furutani H., Yamamoto K., Kitazoe Y. Online support functions of prescription order system and prescription audit in an integrated hospital information system. Med Inform (Lond) 1988 Jul-Sep;13(3):161–169. doi: 10.3109/14639238809010097. [DOI] [PubMed] [Google Scholar]
- Ogura H., Sagara E., Yamamoto K., Furutani H., Kitazoe Y., Takeda Y. Analysis of the online order entry process in an integrated hospital information system. Comput Biol Med. 1985;15(6):381–393. doi: 10.1016/0010-4825(85)90073-3. [DOI] [PubMed] [Google Scholar]
- Ogura H., Yamamoto K., Furutani H., Kitazoe Y., Hirakawa M., Sagara E. On-line prescription order and prescription support in an integrated hospital information system. Med Inform (Lond) 1985 Oct-Dec;10(4):287–299. doi: 10.3109/14639238509010864. [DOI] [PubMed] [Google Scholar]
- Picart D., Guillois B., Nevo L., Alix D. A program for parenteral and combined parenteral and enteral nutrition of neonates and children in an intensive care unit. Intensive Care Med. 1989;15(4):279–282. doi: 10.1007/BF00271068. [DOI] [PubMed] [Google Scholar]
- Pryor T. A., Gardner R. M., Clayton P. D., Warner H. R. The HELP system. J Med Syst. 1983 Apr;7(2):87–102. doi: 10.1007/BF00995116. [DOI] [PubMed] [Google Scholar]
- Sanders G. D., Lyons E. A. The potential use of expert systems to enable physicians to order more cost-effective diagnostic imaging examinations. J Digit Imaging. 1991 May;4(2):112–122. doi: 10.1007/BF03170419. [DOI] [PubMed] [Google Scholar]
- Schroeder C. G., Pierpaoli P. G. Direct order entry by physicians in a computerized hospital information system. Am J Hosp Pharm. 1986 Feb;43(2):355–359. [PubMed] [Google Scholar]
- Sielaff B. H., Connelly D. P., Scott E. P. ESPRE: a knowledge-based system to support platelet transfusion decisions. IEEE Trans Biomed Eng. 1989 May;36(5):541–546. doi: 10.1109/10.24256. [DOI] [PubMed] [Google Scholar]
- Sittig D. F., Gardner R. M., Morris A. H., Wallace C. J. Clinical evaluation of computer-based respiratory care algorithms. Int J Clin Monit Comput. 1990 Jul;7(3):177–185. doi: 10.1007/BF02915583. [DOI] [PubMed] [Google Scholar]
- Sittig D. F., Pace N. L., Gardner R. M., Beck E., Morris A. H. Implementation of a computerized patient advice system using the HELP clinical information system. Comput Biomed Res. 1989 Oct;22(5):474–487. doi: 10.1016/0010-4809(89)90040-2. [DOI] [PubMed] [Google Scholar]
- Swett H. A., Rothschild M., Weltin G. G., Fisher P. R., Miller P. L. Optimizing radiologic workup: an artificial intelligence approach. J Digit Imaging. 1989 Feb;2(1):15–20. doi: 10.1007/BF03168010. [DOI] [PubMed] [Google Scholar]
- Tierney W. M., McDonald C. J., Hui S. L., Martin D. K. Computer predictions of abnormal test results. Effects on outpatient testing. JAMA. 1988 Feb 26;259(8):1194–1198. [PubMed] [Google Scholar]
- Tierney W. M., McDonald C. J., Martin D. K., Rogers M. P. Computerized display of past test results. Effect on outpatient testing. Ann Intern Med. 1987 Oct;107(4):569–574. doi: 10.7326/0003-4819-107-4-569. [DOI] [PubMed] [Google Scholar]
- Tierney W. M., Miller M. E., McDonald C. J. The effect on test ordering of informing physicians of the charges for outpatient diagnostic tests. N Engl J Med. 1990 May 24;322(21):1499–1504. doi: 10.1056/NEJM199005243222105. [DOI] [PubMed] [Google Scholar]
- Tierney W. M., Miller M. E., Overhage J. M., McDonald C. J. Physician inpatient order writing on microcomputer workstations. Effects on resource utilization. JAMA. 1993 Jan 20;269(3):379–383. [PubMed] [Google Scholar]
- Warner H. R., Olmsted C. M., Rutherford B. D. HELP--a program for medical decision-making. Comput Biomed Res. 1972 Feb;5(1):65–74. doi: 10.1016/0010-4809(72)90007-9. [DOI] [PubMed] [Google Scholar]
- White K. S., Lindsay A., Pryor T. A., Brown W. F., Walsh K. Application of a computerized medical decision-making process to the problem of digoxin intoxication. J Am Coll Cardiol. 1984 Sep;4(3):571–576. doi: 10.1016/s0735-1097(84)80104-7. [DOI] [PubMed] [Google Scholar]