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. 1980 Sep 1;189(3):407–412. doi: 10.1042/bj1890407

Quantitative analysis of neutral glycosphingolipids from human lymphocyte subpopulations.

G A Schwarting
PMCID: PMC1162018  PMID: 6971095

Abstract

The glycosphingolipids of normal human lymphocytes from individual donors were analysed by high-pressure liquid chromatography. In addition, purified T- and B-lymphocytes were examined separately. Lactosylceramide was shown to be the major neutral glycosphingolipid in human lymphocytes, and monohexosylceramide, trihexosylceramide, globoside and paragloboside were all detected in smaller amounts. Analysis of purified B- and T-cell fractions revealed that each of these populations contained a similar qualitative profile for neutral glycosphingolipids, but that quantitatively, B-cells contained several times more of each glycosphingolipid per cell than did T-cells.

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Selected References

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